SCHEMBL2822981

SCHEMBL2822981

CCc1ccccc1O[PH](=O)Oc1ccccc1CC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.50
MAPT P10636 2/20 0.50
NPSR1 Q6W5P4 1/20 0.50
HPGD P15428 1/20 0.43
ATM Q13315 1/20 0.43
NISCH Q9Y2I1 1/20 0.42
KDM4E B2RXH2 2/20 0.40
MGLL Q99685 1/20 0.39
GABRA1 P14867 2/20 0.38
GABRB2 P47870 2/20 0.38
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ADRA2A P08913 1/20 0.37
ADRA2B P18089 1/20 0.37
ADRA2C P18825 1/20 0.37
KMT2A Q03164 1/20 0.37
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
IDO1 P14902 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31491509 1.00 L3MBTL1 (0.50) L3MBTL1MAPTNPSR1HPGDATM
SCHEMBL2817836 0.86 HTR1A (0.44) L3MBTL1MAPTNPSR1NISCHADRA2A
SCHEMBL31491508 0.86 HTR1A (0.44) L3MBTL1MAPTNPSR1NISCHADRA2A
SCHEMBL2822983 0.85 L3MBTL1 (0.48) L3MBTL1MAPTNPSR1HPGDATM
SCHEMBL4250541 0.83 L3MBTL1 (0.47) L3MBTL1MAPTNPSR1HPGDATM
SCHEMBL2817841 0.83 THRA (0.47) TAAR1
SCHEMBL1230050 0.82 GABRA1 (0.43) L3MBTL1MAPTNPSR1HPGDATM
SCHEMBL10592927 0.81 THRA (0.52)
SCHEMBL9138458 0.81 EPHX1 (0.41) L3MBTL1MAPTNPSR1HPGDKDM4E
SCHEMBL2818974 0.80 THRA (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4036881-A FROM ALKYLENEAMINE AND ALKANOLAMINE TEXACO DEVELOPMENT CORPORATION (US) 1977-07-19 US claimed
CN-119546668-A Method for producing polyester resin molded body, and master batch 爱天思株式会社 2025-02-28 CN disclosed
US-9920083-B2 Image recording paper medium and image recording method FUJIFILM CORPORATION (JP) 2018-03-20 US disclosed
US-20160250866-A1 IMAGE RECORDING PAPER MEDIUM AND IMAGE RECORDING METHOD FUJIFILM CORPORATION (JP) 2016-09-01 US disclosed
US-8604233-B2 Lubricant composition, magnetic recording medium, and novel polyether compound FUJIFILM CORPORATION (JP) 2013-12-10 US disclosed
US-7812171-B2 Black pigment, black pigment dispersion and black resin composition comprising the same FUJIFILM CORPORATION (JP) 2010-10-12 US disclosed
US-20100247971-A1 LUBRICANT COMPOSITION, MAGNETIC RECORDING MEDIUM, AND NOVEL POLYETHER COMPOUND FUJIFILM CORPORATION (JP) 2010-09-30 US disclosed
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080262237-A1 BLACK PIGMENT, BLACK PIGMENT DISPERSION AND BLACK RESIN COMPOSITION COMPRISING THE SAME FUJIFILM CORPORATION (JP) 2008-10-23 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100247971-A1 LUBRICANT COMPOSITION, MAGNETIC RECORDING MEDIUM, AND NOVEL POLYETHER COMPOUND MUC1, NEFM, CA13 L3MBTL1 3813/4885MAPT 1592/4885NPSR1 578/4885
US-20080262237-A1 BLACK PIGMENT, BLACK PIGMENT DISPERSION AND BLACK RESIN COMPOSITION COMPRISING THE SAME DYNLL1, HNRNPL, AOX1 L3MBTL1 2380/4885MAPT 1184/4885NPSR1 2751/4885
US-20160250866-A1 IMAGE RECORDING PAPER MEDIUM AND IMAGE RECORDING METHOD PHOSPHO1, ITPR2, PPIP5K2 L3MBTL1 4079/4885MAPT 2990/4885NPSR1 853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.