Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450337 | 0.96 | CA1 (0.49) | BIRC2SIRT2SIRT1SIRT3CNR2 | |
| SCHEMBL4169167 | 0.96 | CA1 (0.49) | BIRC2SIRT2SIRT1SIRT3CNR2 | |
| SCHEMBL4169164 | 0.96 | CA1 (0.49) | BIRC2SIRT2SIRT1SIRT3CNR2 | |
| SCHEMBL15048672 | 0.91 | LMNA (0.44) | BIRC2SIRT2CNR2MBOAT4CTRC | |
| SCHEMBL134382 | 0.90 | CTRC (0.48) | BIRC2CNR2CTRCCETPMMP2 | |
| SCHEMBL134381 | 0.90 | CTRC (0.48) | BIRC2CNR2CTRCCETPMMP2 | |
| SCHEMBL8054966 | 0.88 | CTRC (0.50) | CNR2CTRCCETPMMP2MMP1 | |
| SCHEMBL15048738 | 0.87 | HSD17B10 (0.46) | CNR2CETPALDH1A1CYP3A4TSHR | |
| SCHEMBL3319286 | 0.85 | PTGES (0.48) | CNR2CA2CTRCALDH1A1TSHR | |
| SCHEMBL4955699 | 0.85 | PTGES (0.48) | CNR2CA2CTRCALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130177963-A1 | ASYMMETRIC HYDROLASE AND GENE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-11 | — | — | US | disclosed |
| EP-2607480-A1 | Asymmetric hydrolase and gene thereof | Sumitomo Chemical Company, Limited (JP) | 2013-06-26 | — | — | EP | disclosed |