Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450337 | 1.00 | CA1 (0.49) | CA1CA2BIRC2CTSLCTSS | |
| SCHEMBL4169164 | 1.00 | CA1 (0.49) | CA1CA2BIRC2CTSLCTSS | |
| SCHEMBL15048701 | 0.96 | BIRC2 (0.49) | CA1CA2BIRC2CNR2TSHR | |
| SCHEMBL15048738 | 0.91 | HSD17B10 (0.46) | CTSLCTSSCNR2TSHRALDH1A1 | |
| SCHEMBL4955699 | 0.89 | PTGES (0.48) | CA2CTSLCTSSCNR2TSHR | |
| SCHEMBL3319286 | 0.89 | PTGES (0.48) | CA2CTSLCTSSCNR2TSHR | |
| SCHEMBL15048672 | 0.87 | LMNA (0.44) | BIRC2CNR2TSHRL3MBTL1MBOAT4 | |
| SCHEMBL134381 | 0.85 | CTRC (0.48) | BIRC2CNR2FOLH1PTGESALOX5 | |
| SCHEMBL134382 | 0.85 | CTRC (0.48) | BIRC2CNR2FOLH1PTGESALOX5 | |
| SCHEMBL8054966 | 0.84 | CTRC (0.50) | CNR2CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131707-A1 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2009-05-21 | — | — | US | claimed |
| US-20090131707-A1 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2009-05-21 | — | — | US | disclosed |
| US-7452999-B2 | Chemical process for the preparation of intermediates to obtain N-formyl hydroxy-lamine compounds | NOVARTIS AG (CH) | 2008-11-18 | — | — | US | disclosed |
| US-20070179298-A1 | Chemical process for the preparation of intermediates to obtain n-formyl hydroxy-lamine compounds | NOVARTIS AG (CH) | 2007-08-02 | — | — | US | disclosed |
| EP-1599440-A2 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | Novartis AG (CH) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004076053-A2 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2004-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131707-A1 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | HAO2, HAO1, HAAO | CA1 4268/4885CA2 4279/4885BIRC2 2635/4885 |
| US-20070179298-A1 | Chemical process for the preparation of intermediates to obtain n-formyl hydroxy-lamine compounds | HAO1, LMNA, HAO2 | CA1 4869/4885CA2 4853/4885BIRC2 2885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.