Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15048672 | 0.96 | LMNA (0.44) | HSD17B10TSHRKDM4EL3MBTL1LMNA | |
| SCHEMBL6450337 | 0.91 | CA1 (0.49) | HSD17B10TSHRKDM4EL3MBTL1CTSL | |
| SCHEMBL4169164 | 0.91 | CA1 (0.49) | HSD17B10TSHRKDM4EL3MBTL1CTSL | |
| SCHEMBL4169167 | 0.91 | CA1 (0.49) | HSD17B10TSHRKDM4EL3MBTL1CTSL | |
| SCHEMBL4955699 | 0.88 | PTGES (0.48) | HSD17B10TSHRKDM4ECTSLCTSS | |
| SCHEMBL3319286 | 0.88 | PTGES (0.48) | HSD17B10TSHRKDM4ECTSLCTSS | |
| SCHEMBL15048701 | 0.87 | BIRC2 (0.49) | TSHRL3MBTL1CNR2TDP1ALDH1A1 | |
| SCHEMBL134381 | 0.84 | CTRC (0.48) | CNR2PPARGPTGESALOX5CETP | |
| SCHEMBL134382 | 0.84 | CTRC (0.48) | CNR2PPARGPTGESALOX5CETP | |
| SCHEMBL8054966 | 0.83 | CTRC (0.50) | CNR2CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130177963-A1 | ASYMMETRIC HYDROLASE AND GENE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-11 | — | — | US | disclosed |
| EP-2607480-A1 | Asymmetric hydrolase and gene thereof | Sumitomo Chemical Company, Limited (JP) | 2013-06-26 | — | — | EP | disclosed |