SCHEMBL15048747

SCHEMBL15048747

CCCCCCCCC(O)C=CC=CC=CC=CC=CC(=O)O

nearest known ligand 0.84

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.84
BACE1 P56817 1/20 0.84
PPARG P37231 2/20 0.60
FPR2 P25090 2/20 0.60
GPR132 Q9UNW8 1/20 0.60
NFKB1 P19838 1/20 0.60
NFKB2 Q00653 1/20 0.60
RELA Q04206 1/20 0.60
MAPT P10636 2/20 0.59
TRPA1 O75762 1/20 0.59
DDAH1 O94760 1/20 0.59
GAPDH P04406 1/20 0.59
OXER1 Q8TDS5 1/20 0.58
LTB4R2 Q9NPC1 2/20 0.54
LTB4R Q15722 2/20 0.54
ALDH1A1 P00352 1/20 0.54
ALOX5 P09917 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1374447 1.00 ACHE (0.84) ACHEBACE1PPARGFPR2GPR132
SCHEMBL1141419 1.00 ACHE (0.84) ACHEBACE1PPARGFPR2GPR132
SCHEMBL1141420 1.00 ACHE (0.84) ACHEBACE1PPARGFPR2GPR132
SCHEMBL1377741 1.00 ACHE (0.84) ACHEBACE1PPARGFPR2GPR132
SCHEMBL3089267 1.00 ACHE (0.84) ACHEBACE1PPARGFPR2GPR132
SCHEMBL25330257 1.00 ACHE (0.84) ACHEBACE1PPARGFPR2GPR132
SCHEMBL3089270 1.00 ACHE (0.84) ACHEBACE1PPARGFPR2GPR132
SCHEMBL3969741 1.00 ACHE (0.84) ACHEBACE1PPARGFPR2GPR132
SCHEMBL28194553 0.98 ACHE (0.87) ACHEBACE1PPARGFPR2GPR132
SCHEMBL25331522 0.95 ACHE (0.77) ACHEBACE1PPARGFPR2GPR132

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676460-A1 COMPOSITIONS COMPRISING 15-HEPE AND METHODS OF TREATING AND/OR PREVENTING HEMATOLOGIC DISORDERS AND RELATED DISEASES Afimmune Limited (IE) 2026-01-14 EP claimed
EP-4468884-A1 LYMPH-RELEASING COMPOSITIONS OF FATTY ACIDS AND USES THEREOF FOR LYMPHATIC INCORPORATION AND SYSTEMIC DISEASE TREATMENT Amarin Pharmaceuticals Ireland Limited (IE) 2024-12-04 EP claimed
CN-118714935-A Lymphoreleased fatty acid compositions and their use for lymphatic incorporation and systemic disease treatment 阿马里纳药物爱尔兰有限公司 2024-09-27 CN claimed
US-20240299328-A1 COMPOSITIONS COMPRISING 15-HEPE AND METHODS OF TREATING AND/OR PREVENTING HEMATOLOGIC DISORDERS AND RELATED DISEASES AFIMMUNE LIMITED (IE) 2024-09-12 US claimed
WO-2024184383-A1 COMPOSITIONS COMPRISING 15-HEPE AND METHODS OF TREATING AND/OR PREVENTING HEMATOLOGIC DISORDERS AND RELATED DISEASES AFIMMUNE LIMITED (IE) 2024-09-12 WO claimed
US-20240173285-A1 COMPOSITIONS COMPRISING EPA AND METHODS OF USING THE SAME FOR TREATING AND/OR PREVENTING ENDOTHELIAL DYSFUNCTION IN A SUBJECT AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) 2024-05-30 US claimed
EP-4329742-A1 COMPOSITIONS COMPRISING EPA AND METHODS OF USING THE SAME FOR TREATING AND/OR PREVENTING ENDOTHELIAL DYSFUNCTION IN A SUBJECT Amarin Pharmaceuticals Ireland Limited (IE) 2024-03-06 EP claimed
CN-116848260-A Enzyme-based preparation of specific pro-inflammatory regressive mediators (SPMs) by docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) 赢创运营有限公司 2023-10-03 CN claimed
WO-2023146984-A1 LYMPH-RELEASING COMPOSITIONS OF FATTY ACIDS AND USES THEREOF FOR LYMPHATIC INCORPORATION AND SYSTEMIC DISEASE TREATMENT AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) 2023-08-03 WO claimed
US-10010492-B2 Methods and compositions for treating skin to resolve inflammation and screening for actives that stimulate pro-resolution pathways ELC MANAGEMENT LLC (US) 2018-07-03 US claimed
US-20170319451-A1 Methods And Compositions For Treating Skin To Resolve Inflammation And Screening For Actives That Stimulate Pro-Resolution Pathways ELC MAN LLC (US) 2017-11-09 US claimed
US-9682034-B2 Methods and compositions for treating skin to resolve inflammation and screening for actives that stimulate pro-resolution pathways ELC MANAGEMENT LLC (US) 2017-06-20 US claimed
US-20130274327-A1 NOVEL ANTI-INFLAMMATORY METABOLITE DERIVED FROM OMEGA-3-TYPE FATTY ACID THE UNIVERSITY OF TOKYO (JP) 2013-10-17 US claimed
EP-2607358-A1 NOVEL ANTI-INFLAMMATORY METABOLITE DERIVED FROM OMEGA-3-TYPE FATTY ACID The University of Tokyo (JP) 2013-06-26 EP claimed
EP-4007500-B1 PREPARATION COMPRISING OMEGA-3 FATTY ACID SALTS AND EXTRACTS OF GUM RESINS FROM BOSWELLIA SPECIES EVONIK OPERATIONS GMBH (DE) 2026-03-25 EP disclosed
US-20260041696-A1 IN-SITU PRODUCTION OF ANTI-INFLAMMATORY LIPIDS USING MILK FAT GLOBULES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-02-12 US disclosed
EP-4676460-A1 COMPOSITIONS COMPRISING 15-HEPE AND METHODS OF TREATING AND/OR PREVENTING HEMATOLOGIC DISORDERS AND RELATED DISEASES Afimmune Limited (IE) 2026-01-14 EP disclosed
WO-2013170006-A2 OILS WITH ANTI-INFLAMMATORY ACTIVITY CONTAINING NATURAL SPECIALIZED PRORESOLVING MEDIATORS AND THEIR PRECURSORS SOLUTEX NA LLC (US) 2013-11-14 WO disclosed
US-20130274327-A1 NOVEL ANTI-INFLAMMATORY METABOLITE DERIVED FROM OMEGA-3-TYPE FATTY ACID THE UNIVERSITY OF TOKYO (JP) 2013-10-17 US disclosed
EP-2607358-A1 NOVEL ANTI-INFLAMMATORY METABOLITE DERIVED FROM OMEGA-3-TYPE FATTY ACID The University of Tokyo (JP) 2013-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10010492-B2 Methods and compositions for treating skin to resolve inflammation and screening for actives that stimulate pro-resolution pathways ALOX15B, ALOX12, ALOX15 ACHE 1026/4885BACE1 904/4885PPARG 286/4885
US-20260041696-A1 IN-SITU PRODUCTION OF ANTI-INFLAMMATORY LIPIDS USING MILK FAT GLOBULES ALOX5, ALOX15, ALOX15B ACHE 2692/4885BACE1 4477/4885PPARG 202/4885
US-20130274327-A1 NOVEL ANTI-INFLAMMATORY METABOLITE DERIVED FROM OMEGA-3-TYPE FATTY ACID PTGES3, ALOX5, ALOX15 ACHE 2996/4885BACE1 2859/4885PPARG 166/4885
US-20170319451-A1 Methods And Compositions For Treating Skin To Resolve Inflammation And Screening For Actives That Stimulate Pro-Resolution Pathways ALOX15B, ALOX12, ALOX15 ACHE 1026/4885BACE1 904/4885PPARG 286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.