Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15061846 | 0.93 | PTGS2 (0.49) | PTGS2ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL15048757 | 0.93 | PTGS2 (0.49) | PTGS2ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL14988906 | 0.85 | PTGS2 (0.55) | PTGS2ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL2612522 | 0.82 | PTGS2 (0.70) | PTGS2ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL14988996 | 0.79 | PTGS2 (0.56) | PTGS2ADRB2ADRB1ADRB3KDM4E | |
| Glycerol Phenylbutyrate SCHEMBL10102804 | 0.79 | ADRB2 (0.56) | ADRB2ADRB1ADRB3LMNAALDH1A1 | |
| SCHEMBL13809623 | 0.79 | PTGS2 (0.62) | PTGS2ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL22924945 | 0.78 | PTGS2 (0.47) | PTGS2KDM4EHSD17B10LMNACYP1A2 | |
| SCHEMBL7360282 | 0.77 | KDM4E (0.57) | ADRB2ADRB1ADRB3KDM4EHSD17B10 | |
| SCHEMBL20643712 | 0.77 | PTGS2 (0.47) | PTGS2KDM4EHSD17B10LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607366-A1 | Glycerol phenyl butyrate esters | Lunamed AG (CH) | 2013-06-26 | — | — | EP | disclosed |
| EP-2607366-A1 | Glycerol phenyl butyrate esters | Lunamed AG (CH) | 2013-06-26 | — | — | EP | disclosed |