Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16876670 | 0.80 | LMNA (0.44) | LMNACYP1A2ALDH1A1TSHRTDP1 | |
| SCHEMBL5941140 | 0.79 | PTGS2 (0.44) | PTGS2KDM4EHSD17B10LMNACYP1A2 | |
| SCHEMBL15048752 | 0.78 | PTGS2 (0.56) | PTGS2KDM4EHSD17B10LMNACYP1A2 | |
| SCHEMBL1114532 | 0.76 | PTGS2 (0.64) | PTGS2KDM4EHSD17B10LMNACYP1A2 | |
| SCHEMBL3378708 | 0.75 | PTGS2 (0.60) | PTGS2KDM4EHSD17B10LMNACYP1A2 | |
| SCHEMBL4731408 | 0.75 | PTGS2 (0.56) | PTGS2KDM4EHSD17B10LMNACYP1A2 | |
| SCHEMBL20643712 | 0.75 | PTGS2 (0.47) | PTGS2KDM4EHSD17B10LMNACYP1A2 | |
| SCHEMBL29626977 | 0.74 | ALDH1A1 (0.55) | PTGS2LMNAALDH1A1TSHRMAPK1 | |
| SCHEMBL17539124 | 0.74 | ALDH1A1 (0.55) | PTGS2LMNAALDH1A1TSHRMAPK1 | |
| SCHEMBL15061846 | 0.74 | PTGS2 (0.49) | PTGS2KDM4EHSD17B10LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210024686-A1 | POLY(GLYCEROL SEBACATE)-INTERLEUKIN INHIBITOR COPOLYMERS AND METHODS OF MAKING AND USE | JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT | 2021-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210024686-A1 | POLY(GLYCEROL SEBACATE)-INTERLEUKIN INHIBITOR COPOLYMERS AND METHODS OF MAKING AND USE | IL2, IL17A, IL6 | PTGS2 108/4885KDM4E 4127/4885HSD17B10 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.