SCHEMBL4347089

SCHEMBL4347089

NC(=O)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CC(N)=O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 3/20 0.53
ITGB2 P05107 2/20 0.43
ICAM1 P05362 2/20 0.43
ITGAL P20701 2/20 0.43
PDCD1LG2 Q9BQ51 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
CA2 P00918 4/20 0.41
CA1 P00915 3/20 0.41
ALDH1A1 P00352 1/20 0.41
RAB9A P51151 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CTSD P07339 1/20 0.39
BACE1 P56817 1/20 0.39
GNPAT O15228 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1246595 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL9752652 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL757072 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL6852847 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL6136566 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL7148009 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL7258586 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL150536 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL31182997 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL18075525 0.96 ECE1 (0.56) ECE1ITGB2ICAM1ITGALPDCD1LG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0542845-A1 PLASMODIUM FALCIPARUM ANTIGEN FOR ELICITING PROTECTIVE ANTIBODIES FOR USE IN VACCINES. PASTEUR INSTITUT (FR) 1993-05-26 EP claimed
CN-112166188-B Method for producing ethanol using engineered yeast 嘉吉有限公司 2024-07-02 CN disclosed
CN-111471719-B Efficient non-meiotic allele introgression 重组股份有限公司 2024-06-18 CN disclosed
CN-110628729-B Baculovirus and composition for detecting and preventing porcine epidemic diarrhea virus infection 周美吟 2024-05-28 CN disclosed
CN-113826013-B Polypeptide magnetic nanoparticle, preparation method and application thereof 北京中科纳泰生物科技有限公司 2024-05-24 CN disclosed
CN-117858945-A Modification of HECT E3 ubiquitin ligase gene for improved yield traits 成对植物服务股份有限公司 2024-04-09 CN disclosed
CN-111983220-B Polypeptide magnetic nanoparticle, preparation method and application thereof 北京中科纳泰生物科技有限公司 2024-03-19 CN disclosed
CN-110582567-B Genetically modified trehalase-expressing yeasts and fermentation methods using such genetically modified yeasts 嘉吉公司 2024-03-08 CN disclosed
CN-112996803-B Phosphoric acid transposition device BIOC3公司 2024-02-13 CN disclosed
CN-111979162-B Recombinant bacillus calmette-guerin strain, preparation method and application thereof 上海市公共卫生临床中心 2024-02-13 CN disclosed
US-5342755-A Complexing with streptokinase and lactate dehydrogenase GEORGETOWN UNIVERSITY (US) 1994-08-30 US disclosed
WO-1994017187-A1 CLONING AND EXPRESSION OF PLASMODIUM FALCIPARUM TRANSMISSION-BLOCKING TARGET ANTIGEN, Pfs230 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1994-08-04 WO disclosed
EP-0542845-A1 PLASMODIUM FALCIPARUM ANTIGEN FOR ELICITING PROTECTIVE ANTIBODIES FOR USE IN VACCINES. PASTEUR INSTITUT (FR) 1993-05-26 EP disclosed
WO-1993009235-A2 UBIQUITIN-SPECIFIC PROTEASES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1993-05-13 WO disclosed
WO-1993003057-A1 POLYPEPTIDES CAPABLE OF IN VIVO INDUCTION OF ANTIBODIES THEMSELVES CAPABLE OF INHIBITING THE INVASION OF RED BLOOD CORPUSCLES BY MEROZOITES OF P.FALCIPARUM, RELATED PRODUCTS AND THEIR USE IN PRODUCING VACCINE COMPOSITIONS INSTITUT PASTEUR (FR) 1993-02-18 WO disclosed
WO-1993002704-A1 MIXTURE OF PEPTIDE CONSTITUENTS HAVING VACCINATING PROPERTIES AGAINST PALUDISM PARTICULARLY DUE TO PLASMODIUM FALCIPARUM INSTITUT PASTEUR (FR) 1993-02-18 WO disclosed
WO-1992002549-A1 PLASMODIUM FALCIPARUM ANTIGEN FOR ELICITING PROTECTIVE ANTIBODIES FOR USE IN VACCINES INSTITUT PASTEUR (FR) 1992-02-20 WO disclosed
WO-1991008756-A1 NOVEL MALARIAL SPOROZOITE PEPTIDE ANTIGENS BIOMEDICAL RESEARCH INSTITUTE (US) 1991-06-27 WO disclosed
WO-1988008165-A1 COMPUTER BASED METHOD FOR PROTEIN ENGINEERING GENEX CORPORATION (US) 1988-10-20 WO disclosed
WO-1988008164-A1 COMPUTER DESIGNED STABILIZED PROTEINS AND METHOD FOR PRODUCING SAME GENEX CORPORATION (US) 1988-10-20 WO disclosed