SCHEMBL757072

SCHEMBL757072

NC(=O)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CC(N)=O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 3/20 0.53
ITGB2 P05107 2/20 0.43
ICAM1 P05362 2/20 0.43
ITGAL P20701 2/20 0.43
PDCD1LG2 Q9BQ51 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
CA2 P00918 4/20 0.41
CA1 P00915 3/20 0.41
ALDH1A1 P00352 1/20 0.41
RAB9A P51151 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CTSD P07339 1/20 0.39
BACE1 P56817 1/20 0.39
GNPAT O15228 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4347089 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL1246595 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL9752652 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL6852847 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL6136566 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL7148009 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL7258586 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL150536 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL31182997 1.00 ECE1 (0.53) ECE1ITGB2ICAM1ITGALPDCD1LG2
SCHEMBL18075525 0.96 ECE1 (0.56) ECE1ITGB2ICAM1ITGALPDCD1LG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3668874-A1 PYRROLOBENZODIAZEPINE CONJUGATES Medimmune Limited (GB) 2020-06-24 EP claimed
WO-2019034764-A1 PYRROLOBENZODIAZEPINE CONJUGATES MEDIMMUNE LIMITED (GB) 2019-02-21 WO claimed
CN-102399792-A Cloning identification of GhNAC1 gene related to development of secondary wall of cotton fiber cell UNIV HUAZHONG NORMAL 2012-04-04 CN claimed
US-20250345411-A1 VACCINATION IN NEWBORNS AND INFANTS CureVac SE (DE) 2025-11-13 US disclosed
US-20250345410-A1 VACCINATION IN NEWBORNS AND INFANTS CureVac SE (DE) 2025-11-13 US disclosed
US-12390520-B2 Vaccination in newborns and infants Cure Vac SE (DE) 2025-08-19 US disclosed
US-20240390478-A1 VACCINATION IN ELDERLY PATIENTS CureVac SE (DE) 2024-11-28 US disclosed
US-12036277-B2 Vaccination with mRNA-coded antigens CureVac SE (DE) 2024-07-16 US disclosed
CN-111989113-B Pharmaceutical composition for treating cancer comprising guide RNA and endonuclease as active ingredients G+FLAS生命科学有限公司 2024-07-12 CN disclosed
CN-113710801-B Novel immuno-PCR method using cDNA display 爱普思隆分子进化工程株式会社 2024-07-09 CN disclosed
US-20240197857-A1 VACCINATION WITH mRNA-CODED ANTIGENS CureVac SE (DE) 2024-06-20 US disclosed
WO-1994003075-A2 MORPHOGEN-ENRICHED DIETARY COMPOSITION CREATIVE BIOMOLECULES, INC. (US) 1994-02-17 WO disclosed
WO-1993025246-A1 PROSTHETIC DEVICES HAVING ENHANCED OSTEOGENIC PROPERTIES STRYKER CORPORATION (US) 1993-12-23 WO disclosed
EP-0573613-A1 ENTOMOPOXVIRUS EXPRESSION SYSTEM COMPRISING SPHEROIDIN OR THYMIDINE-KINASE SEQUENCES UNIVERSITY OF FLORIDA (US) 1993-12-15 EP disclosed
WO-1993013222-A1 DNA STRUCTURE-SPECIFIC RECOGNITION PROTEIN AND USES THEREFOR MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1993-07-08 WO disclosed
WO-1993010250-A1 TRANSCRIPTION ADAPTORS IN EUKARYOTES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1993-05-27 WO disclosed
WO-1993009235-A2 UBIQUITIN-SPECIFIC PROTEASES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1993-05-13 WO disclosed
WO-1993009143-A1 PRODUCTION AND USE OF MULTIMERIC HEMOGLOBINS SOMATOGEN, INC. (US) 1993-05-13 WO disclosed
WO-1992014818-A2 ENTOMOPOXVIRUS EXPRESSION SYSTEM COMPRISING SPHEROIDIN OR THYMIDINE-KINASE SEQUENCES UNIVERSITY OF FLORIDA (US) 1992-09-03 WO disclosed
WO-1992010518-A1 PURIFIED SLIT PROTEIN AND SEQUENCE ELEMENTS THEREOF YALE UNIVERSITY (US) 1992-06-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250345410-A1 VACCINATION IN NEWBORNS AND INFANTS HLA-DRB1, TLR3, TLR9 ECE1 4185/4885ITGB2 1716/4885ICAM1 3642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.