Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KYNU | Q16719 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.55 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 6/20 | 0.54 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15055671 | 1.00 | KYNU (0.60) | KYNUALDH1A1ALOX15SIRT2SIRT1 | |
| SCHEMBL1111004 | 0.93 | SIRT2 (0.60) | KYNUALDH1A1ALOX15SIRT2SIRT1 | |
| SCHEMBL1111001 | 0.93 | SIRT2 (0.60) | KYNUALDH1A1ALOX15SIRT2SIRT1 | |
| SCHEMBL1111018 | 0.93 | SIRT2 (0.60) | KYNUALDH1A1ALOX15SIRT2SIRT1 | |
| SCHEMBL22144256 | 0.92 | CTSK (0.53) | KYNUALDH1A1ALOX15CTSKCTSS | |
| SCHEMBL17860731 | 0.92 | CTSK (0.53) | KYNUALDH1A1ALOX15CTSKCTSS | |
| SCHEMBL1200288 | 0.89 | KYNU (0.63) | KYNUALDH1A1ALOX15CTSKCTSS | |
| SCHEMBL2980857 | 0.89 | KYNU (0.63) | KYNUALDH1A1ALOX15CTSKCTSS | |
| SCHEMBL8386880 | 0.89 | SIRT2 (0.67) | KYNUALDH1A1ALOX15SIRT2SIRT1 | |
| SCHEMBL6543239 | 0.89 | PPARA (0.54) | ALDH1A1ALOX15SIRT2SIRT1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8822516-B2 | Process for the preparation of iodides | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2014-09-02 | — | — | US | disclosed |
| US-8822516-B2 | Process for the preparation of iodides | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2014-09-02 | — | — | US | disclosed |
| US-20130165658-A1 | PROCESS FOR THE PREPARATION OF IODIDES | TECHNION R&D FOUNDATION LTD. (IL) | 2013-06-27 | — | — | US | disclosed |
| US-20130165658-A1 | PROCESS FOR THE PREPARATION OF IODIDES | TECHNION R&D FOUNDATION LTD. (IL) | 2013-06-27 | — | — | US | disclosed |
| WO-2011154953-A1 | PROCESS FOR THE PREPARATION OF IODIDES | TECHNION R&D FOUNDATION LTD. (IL) | 2011-12-15 | — | — | WO | disclosed |
| WO-2011154953-A1 | PROCESS FOR THE PREPARATION OF IODIDES | TECHNION R&D FOUNDATION LTD. (IL) | 2011-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165658-A1 | PROCESS FOR THE PREPARATION OF IODIDES | NISCH, TPO, HDHD5 | KYNU 885/4885ALDH1A1 281/4885ALOX15 1253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.