Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15059575 | 0.74 | LMNA (0.35) | LMNASMN1; SMN2GLA | |
| SCHEMBL3664875 | 0.68 | HTR2C (0.34) | — | |
| SCHEMBL28102330 | 0.66 | LMNA (0.36) | LMNASMN1; SMN2GLA | |
| SCHEMBL15057744 | 0.65 | GABRP (0.31) | LMNA | |
| SCHEMBL3664878 | 0.64 | HTR2C (0.35) | LMNA | |
| SCHEMBL2038482 | 0.64 | — | — | |
| SCHEMBL18398429 | 0.62 | ADORA1 (0.31) | — | |
| SCHEMBL27233080 | 0.62 | NAMPT (0.33) | LMNA | |
| SCHEMBL17376353 | 0.62 | QDPR (0.34) | — | |
| SCHEMBL17837793 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794587-A1 | NEW PIPERIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013092976-A1 | NEW PIPERIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-27 | — | — | WO | disclosed |