Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17744822 | 0.88 | MMP2 (0.57) | ALDH1A1MAPTLMNAMYCL3MBTL1 | |
| SCHEMBL17744779 | 0.86 | MMP2 (0.55) | ALDH1A1MAPTLMNAMYCL3MBTL1 | |
| SCHEMBL11230003 | 0.82 | ACMSD (0.54) | ALDH1A1MAPTLMNAMYCL3MBTL1 | |
| SCHEMBL15060460 | 0.81 | G6PD (0.55) | ALDH1A1MAPTLMNAMYCL3MBTL1 | |
| SCHEMBL28166012 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNAMYCL3MBTL1 | |
| SCHEMBL3824307 | 0.80 | MYC (0.67) | ALDH1A1MAPTLMNAMYCL3MBTL1 | |
| SCHEMBL10527823 | 0.80 | MYC (0.57) | ALDH1A1MAPTLMNAMYCL3MBTL1 | |
| SCHEMBL3824168 | 0.80 | FABP4 (0.48) | ALDH1A1MAPTLMNAMYCL3MBTL1 | |
| SCHEMBL4256428 | 0.79 | ALB (0.52) | ALDH1A1MAPTLMNAMYCL3MBTL1 | |
| SCHEMBL16055261 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAMYCL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103649053-B | Aminomethyl quinolone compounds | 霍夫曼-拉罗奇有限公司 | 2017-07-04 | — | — | CN | disclosed |
| WO-2013096153-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2013-06-27 | — | — | WO | disclosed |