Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | VEGFA | P15692 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL740369 | 0.93 | CA1 (0.34) | KDM4EALDH1A1CA1CA2LMNA | |
| SCHEMBL738538 | 0.92 | CYP3A4 (0.38) | ALDH1A1CA1CA2ELOVL6CYP3A4 | |
| SCHEMBL12846265 | 0.92 | HDAC4 (0.38) | EGLN1KDM4EALDH1A1VEGFAFLT1 | |
| SCHEMBL739739 | 0.92 | EGLN1 (0.36) | EGLN1KDM4EALDH1A1VEGFAFLT1 | |
| SCHEMBL29175527 | 0.91 | CA1 (0.32) | CA1CA2ORAI1 | |
| SCHEMBL15059546 | 0.91 | TTK (0.36) | CA1CA2LMNAELOVL6ORAI1 | |
| SCHEMBL15059547 | 0.91 | TTK (0.36) | CA1CA2LMNAELOVL6ORAI1 | |
| SCHEMBL12846266 | 0.91 | HDAC4 (0.38) | KDM4ECA1CA2LMNAL3MBTL1 | |
| SCHEMBL12846262 | 0.91 | TTK (0.33) | KDM4ECA1CA2ELOVL6CYP3A4 | |
| SCHEMBL30233680 | 0.91 | CASP1 (0.39) | KDM4EALDH1A1RAB9ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077285-A1 | PROCESS FOR PREPARING FLURALANER | KRKA, d.d., Novo mesto (SI) | 2022-10-26 | — | — | EP | claimed |
| WO-2021122356-A1 | PROCESS FOR PREPARING FLURALANER | KRKA, D.D., NOVO MESTO (SI) | 2021-06-24 | — | — | WO | claimed |
| US-20250091998-A1 | A PROCESS FOR THE PREPARATION OF CARBAMOYL BENZAMIDE PHENYL ISOXAZOLINE CLASS DRUG/S AND ITS INTERMEDIATES | ZENFOLD SUSTAINABLE TECHNOLOGIES PRIVATE LIMITED (IN) | 2025-03-20 | — | — | US | disclosed |
| US-11878006-B2 | Isoxazoline solution containing vitamin E for use with sanitized drinking water | INTERVET INC. (US) | 2024-01-23 | — | — | US | disclosed |
| US-20230355590-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2023-11-09 | — | — | US | disclosed |
| WO-2023012821-A1 | A PROCESS FOR THE PREPARATION OF CARBAMOYL BENZAMIDE PHENYL ISOXAZOLINE CLASS DRUG/S AND ITS INTERMEDIATES | ZENFOLD SUSTAINABLE TECHNOLOGIES PRIVATE LIMITED (IN) | 2023-02-09 | — | — | WO | disclosed |
| WO-2023012821-A1 | A PROCESS FOR THE PREPARATION OF CARBAMOYL BENZAMIDE PHENYL ISOXAZOLINE CLASS DRUG/S AND ITS INTERMEDIATES | ZENFOLD SUSTAINABLE TECHNOLOGIES PRIVATE LIMITED (IN) | 2023-02-09 | — | — | WO | disclosed |
| EP-4077285-A1 | PROCESS FOR PREPARING FLURALANER | KRKA, d.d., Novo mesto (SI) | 2022-10-26 | — | — | EP | disclosed |
| EP-3313400-B1 | ISOXAZOLINE SOLUTION CONTAINING VITAMIN E FOR USE WITH SANITIZED DRINKING WATER | INTERVET INT BV (NL) | 2022-06-15 | — | — | EP | disclosed |
| US-11179372-B2 | Isoxazoline solution containing vitamin E for use with sanitized drinking water | INTERVET INC. (US) | 2021-11-23 | — | — | US | disclosed |
| US-11179372-B2 | Isoxazoline solution containing vitamin E for use with sanitized drinking water | INTERVET INC. (US) | 2021-11-23 | — | — | US | disclosed |
| US-20120172615-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-07-05 | — | — | US | disclosed |
| US-8138213-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-03-20 | — | — | US | disclosed |
| WO-2011157733-A2 | NEW USE | NOVARTIS AG (CH) | 2011-12-22 | — | — | WO | disclosed |
| US-20110251398-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-10-13 | — | — | US | disclosed |
| US-8022089-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-09-20 | — | — | US | disclosed |
| US-7662972-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-20090312330-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-12-17 | — | — | US | disclosed |
| US-20070066617-A1 | Insecticidal and acaricidal activity for many agricultural insect pests, spider mites; endo- or ecto-parasiticide for mammals or birds; veterinary medicine; environmentally friendly | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-03-22 | — | — | US | disclosed |
| EP-1731512-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2006-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230355590-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | HDAC7, ACHE, BRDT | EGLN1 721/4885KDM4E 1334/4885ALDH1A1 865/4885 |
| US-11179372-B2 | Isoxazoline solution containing vitamin E for use with sanitized drinking water | PROC, EPX, CYP27B1 | EGLN1 96/4885KDM4E 1326/4885ALDH1A1 243/4885 |
| US-20120172615-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | C3AR1, C5, C9 | EGLN1 966/4885KDM4E 3525/4885ALDH1A1 3702/4885 |
| US-11878006-B2 | Isoxazoline solution containing vitamin E for use with sanitized drinking water | PROC, EPX, CYP27B1 | EGLN1 96/4885KDM4E 1326/4885ALDH1A1 243/4885 |
| US-20250091998-A1 | A PROCESS FOR THE PREPARATION OF CARBAMOYL BENZAMIDE PHENYL ISOXAZOLINE CLASS DRUG/S AND ITS INTERMEDIATES | CYP3A7, CYP1A2, CYP1B1 | EGLN1 766/4885KDM4E 1260/4885ALDH1A1 266/4885 |
| US-20090312330-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | ATM, CHRM1, NAT1 | EGLN1 661/4885KDM4E 3394/4885ALDH1A1 806/4885 |
| US-20110251398-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | CBR3, CHRM1, CBR1 | EGLN1 2614/4885KDM4E 4330/4885ALDH1A1 1983/4885 |
| US-20070066617-A1 | Insecticidal and acaricidal activity for many agricultural insect pests, spider mites; endo- or ecto-parasiticide for mammals or birds; veterinary medicine; environmentally friendly | CHRM1, DDT, ATM | EGLN1 1504/4885KDM4E 3630/4885ALDH1A1 1359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.