Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL856583 | 0.69 | TP53 (0.53) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13727114 | 0.66 | DPP4 (0.40) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL702012 | 0.62 | CES2 (0.37) | MEN1KMT2A | |
| SCHEMBL30368120 | 0.62 | CES2 (0.37) | MEN1KMT2A | |
| SCHEMBL2114658 | 0.61 | HDAC1 (0.44) | KDM4EALDH1A1CA1CA2 | |
| SCHEMBL4978674 | 0.61 | MEP1B (0.46) | KDM4EALDH1A1CA5ACA5B | |
| SCHEMBL19415705 | 0.60 | CCR2 (0.35) | — | |
| SCHEMBL8043864 | 0.60 | — | — | |
| SCHEMBL19336526 | 0.59 | CCR2 (0.44) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1561647 | 0.59 | TAAR1 (0.36) | CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470818-B2 | Compounds and methods for kinase modulation, and indications therefor | PLEXXIKON INC. (US) | 2013-06-25 | — | — | US | disclosed |