⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24600578 | 0.81 | LTA4H (0.33) | — | |
| SCHEMBL8082469 | 0.77 | MEN1 (0.36) | — | |
| SCHEMBL1609001 | 0.73 | — | — | |
| SCHEMBL2786372 | 0.72 | FBP1 (0.38) | — | |
| SCHEMBL11661489 | 0.71 | DAO (0.41) | — | |
| SCHEMBL28498479 | 0.70 | LMNA (0.33) | — | |
| SCHEMBL12762162 | 0.69 | FBP1 (0.39) | — | |
| SCHEMBL763933 | 0.69 | — | — | |
| SCHEMBL711758 | 0.69 | — | — | |
| SCHEMBL19292761 | 0.68 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009076166-A2 | OXIMYL HCV SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2009-06-18 | — | — | WO | disclosed |
| WO-2008134398-A1 | OXIMYL DIPEPTIDE HEPATITIS C PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |
| WO-2007146695-A1 | ACYCLIC OXIMYL HEPATITIS C PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2007-12-21 | — | — | WO | disclosed |