Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | UBE2M | P61081 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17955425 | 0.83 | KDM4E (0.47) | ALDH1A1KDM4EGAATDP1ATM | |
| SCHEMBL4484154 | 0.78 | OPRL1 (0.61) | ALDH1A1KDM4EGAAATMKMT2A | |
| SCHEMBL11889011 | 0.77 | ALDH1A1 (0.54) | ACHEALDH1A1KDM4EGAATDP1 | |
| SCHEMBL329437 | 0.73 | KMT2A (0.72) | ACHEALDH1A1KDM4EGAATDP1 | |
| SCHEMBL11889055 | 0.72 | ALDH1A1 (0.53) | ACHEALDH1A1KDM4EGAATDP1 | |
| Hydrochloric Acid SCHEMBL23850614 | 0.72 | LMNA (0.71) | ACHEALDH1A1KDM4EGAATDP1 | |
| SCHEMBL1882777 | 0.72 | KMT2A (0.70) | ACHEALDH1A1KDM4EGAATDP1 | |
| SCHEMBL1164984 | 0.72 | KMT2A (0.70) | ACHEALDH1A1KDM4EGAATDP1 | |
| SCHEMBL12856255 | 0.72 | KMT2A (0.76) | ACHEALDH1A1KDM4EGAATDP1 | |
| SCHEMBL12013922 | 0.71 | ACHE (1.00) | ACHEALDH1A1KDM4EKMT2ACYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013091773-A1 | TETRAAZA-CYCLOPENTA[A]INDENYL AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS | MERCK PATENT GMBH (DE) | 2013-06-27 | — | — | WO | disclosed |
| EP-2607364-A1 | Tetraaza-cyclopenta[a]indenyl and their use as positive allosteric modulators | Ares Trading S.A. (CH) | 2013-06-26 | — | — | EP | disclosed |