Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451880 | 0.96 | FKBP1A (0.67) | ALDH1A1FKBP1AMAPK1LMNAMEN1 | |
| SCHEMBL14895147 | 0.96 | FKBP1A (0.67) | ALDH1A1FKBP1AMAPK1LMNAMEN1 | |
| SCHEMBL16164040 | 0.96 | FKBP1A (0.67) | ALDH1A1FKBP1AMAPK1LMNAMEN1 | |
| SCHEMBL14895148 | 0.96 | FKBP1A (0.67) | ALDH1A1FKBP1AMAPK1LMNAMEN1 | |
| SCHEMBL26616321 | 0.86 | ALDH1A1 (0.66) | ALDH1A1FKBP1AMAPK1HTTEPHX2 | |
| SCHEMBL15062616 | 0.84 | FKBP1A (1.00) | ALDH1A1FKBP1AMAPK1LMNAACHE | |
| SCHEMBL14905830 | 0.83 | FKBP1A (0.74) | ALDH1A1FKBP1AMAPK1LMNAMEN1 | |
| SCHEMBL26616350 | 0.82 | MMP2 (0.60) | ALDH1A1FKBP1AHTTACHEKDM4E | |
| SCHEMBL3720939 | 0.82 | MMP2 (0.60) | ALDH1A1FKBP1AHTTACHEKDM4E | |
| SCHEMBL2992157 | 0.81 | ALDH1A1 (0.59) | ALDH1A1FKBP1AMAPK1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150011541-A1 | PIPECOLATE-SULFONAMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2015-01-08 | — | — | US | disclosed |
| EP-2797887-A1 | PIPECOLATE-SULFONAMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013097947-A1 | PIPECOLATE-SULFONAMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-07-04 | — | — | WO | disclosed |
| EP-2610245-A1 | Pipecolate-sulfonamides for treatment of psychiatric disorders | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011541-A1 | PIPECOLATE-SULFONAMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | SYNGR2, SLC18A2, SLC6A3 | ALDH1A1 2630/4885FKBP1A 70/4885MAPK1 3692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.