Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 12/20 | 0.43 |
| ▸ | CTSS | P25774 | 9/20 | 0.43 |
| ▸ | CTSK | P43235 | 9/20 | 0.43 |
| ▸ | CTSB | P07858 | 8/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15062902 | 1.00 | CTSL (0.43) | CTSLCTSSCTSKCTSB | |
| SCHEMBL15062986 | 0.89 | CTSL (0.36) | CTSLCTSSCTSKCTSB | |
| SCHEMBL15062985 | 0.89 | CTSL (0.36) | CTSLCTSSCTSKCTSB | |
| SCHEMBL15062942 | 0.86 | ACE (0.35) | CTSLCTSSCTSKCTSB | |
| SCHEMBL15062943 | 0.86 | ACE (0.35) | CTSLCTSSCTSKCTSB | |
| SCHEMBL2401476 | 0.85 | CTSL (0.53) | CTSLCTSSCTSKCTSB | |
| SCHEMBL2401471 | 0.85 | CTSL (0.53) | CTSLCTSSCTSKCTSB | |
| SCHEMBL15062782 | 0.84 | CTSK (0.41) | CTSLCTSSCTSKCTSB | |
| SCHEMBL2340709 | 0.84 | CTSK (0.41) | CTSLCTSSCTSKCTSB | |
| SCHEMBL15766822 | 0.79 | CTSS (0.47) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361243-B9 | HALOALKYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | VIROBAY INC (US) | 2014-06-11 | — | — | EP | claimed |
| EP-2361243-B1 | HALOALKYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | VIROBAY INC (US) | 2013-07-03 | — | — | EP | claimed |
| EP-2361243-B9 | HALOALKYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | VIROBAY INC (US) | 2014-06-11 | — | — | EP | disclosed |
| EP-2361243-B1 | HALOALKYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | VIROBAY INC (US) | 2013-07-03 | — | — | EP | disclosed |