SCHEMBL15065839

SCHEMBL15065839

FC(F)(F)c1cc([B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc(C(F)(F)F)c1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
TSHR P16473 1/20 0.48
KIF11 P52732 1/20 0.46
P2RX1 P51575 1/20 0.41
IDO1 P14902 1/20 0.41
TDO2 P48775 1/20 0.41
TACR1 P25103 9/20 0.39
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37
METAP2 P50579 1/20 0.37
CACNA1F O60840 1/20 0.37
CACNA1D Q01668 1/20 0.37
CACNA1S Q13698 1/20 0.37
CACNA1C Q13936 1/20 0.37
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
BACE1 P56817 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5909720 1.00 ALDH1A1 (0.48) ALDH1A1TSHRKIF11P2RX1IDO1
Benzene SCHEMBL30336225 0.91 TSHR (0.43) ALDH1A1TSHRKIF11P2RX1IDO1
SCHEMBL22105646 0.89 TAS2R14 (0.40) ALDH1A1TSHRKIF11P2RX1IDO1
SCHEMBL41567 0.86 CES2 (0.44) ALDH1A1TSHRKIF11IDO1RXRA
Aniline SCHEMBL1010731 0.86 ALDH1A1 (0.43) ALDH1A1TSHRKIF11P2RX1IDO1
SCHEMBL25633935 0.85 TAS2R14 (0.40) ALDH1A1TSHRKIF11P2RX1IDO1
SCHEMBL215855 0.84 ALDH1A1 (0.41) ALDH1A1TSHRKIF11P2RX1IDO1
SCHEMBL3244276 0.84 TSHR (0.41) ALDH1A1TSHRKIF11P2RX1IDO1
Toluene SCHEMBL6239727 0.84 TSHR (0.41) ALDH1A1TSHRKIF11P2RX1IDO1
Toluene SCHEMBL6538388 0.84 TSHR (0.41) ALDH1A1TSHRKIF11P2RX1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364382-B2 Curable polysiloxane compositions and pressure sensitive adhesives made therefrom 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-07-30 US disclosed
EP-2797985-B1 CURABLE-ON-DEMAND POLYSILOXANE COATING COMPOSITION 3M INNOVATIVE PROPERTIES CO (US) 2015-09-23 EP disclosed
US-9035008-B2 Curable-on-demand polysiloxane coating composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-05-19 US disclosed
US-20140377494-A1 Curable Polysiloxane Compositions and Pressure Sensitive Adhesives Made Therefrom 3M INNOVATIVE PROPERTIES COMPANY 2014-12-25 US disclosed
US-20140349125-A1 CURABLE-ON-DEMAND POLYSILOXANE COATING COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY 2014-11-27 US disclosed
EP-2797985-A1 CURABLE-ON-DEMAND POLYSILOXANE COATING COMPOSITION 3M Innovative Properties Company (US) 2014-11-05 EP disclosed
EP-2798011-A1 CURABLE POLYSILOXANE COMPOSITIONS AND PRESSURE SENSITIVE ADHESIVES MADE THEREFROM 3M Innovative Properties Company (US) 2014-11-05 EP disclosed
WO-2013101742-A1 CURABLE-ON-DEMAND POLYSILOXANE COATING COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-07-04 WO disclosed
WO-2013101535-A1 CURABLE POLYSILOXANE COMPOSITIONS AND PRESSURE SENSITIVE ADHESIVES MADE THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-07-04 WO disclosed