Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14144110 | 0.94 | NLRP3 (0.57) | NLRP3LMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL473082 | 0.90 | NLRP3 (0.66) | NLRP3LMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL11085743 | 0.88 | SMN1; SMN2 (0.57) | NLRP3LMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL26887084 | 0.86 | NLRP3 (0.61) | NLRP3LMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL1026416 | 0.86 | LMNA (0.61) | NLRP3LMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL11443749 | 0.85 | NLRP3 (0.59) | NLRP3LMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL11399068 | 0.84 | NLRP3 (0.58) | NLRP3LMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL7563975 | 0.84 | NLRP3 (0.58) | NLRP3LMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL11393542 | 0.84 | NLRP3 (0.58) | NLRP3LMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL20414589 | 0.84 | RAB9A (0.53) | NLRP3LMNAALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863440-B2 | Macrocyclic carbodiimides (MC-CDI) and their derivatives, syntheses and applications of the same | GREAT EASTERN RESINS INDUSTRIAL CO., LTD. (TW) | 2011-01-04 | — | — | US | disclosed |
| US-7863440-B2 | Macrocyclic carbodiimides (MC-CDI) and their derivatives, syntheses and applications of the same | GREAT EASTERN RESINS INDUSTRIAL CO., LTD. (TW) | 2011-01-04 | — | — | US | disclosed |
| WO-2008081230-A1 | MACROCYCLIC CARBODIIMIDE (MC-CDI) AND THEIR DERIVATIVES, SYNTHESES AND APPLICATIONS ON THE SAME | GREAT EASTERN RESINS INDUSTRIAL CO., LTD. (US) | 2008-07-10 | — | — | WO | disclosed |
| US-20080161554-A1 | Macrocyclic carbodiimides (MC-CDI) and their derivatives, syntheses and applications of the same | GREAT EASTERN RESINS INDUSTRIAL CO., LTD. (TW) | 2008-07-03 | — | — | US | disclosed |
| US-20080161554-A1 | Macrocyclic carbodiimides (MC-CDI) and their derivatives, syntheses and applications of the same | GREAT EASTERN RESINS INDUSTRIAL CO., LTD. (TW) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161554-A1 | Macrocyclic carbodiimides (MC-CDI) and their derivatives, syntheses and applications of the same | ACMSD, PCNA, UROD | NLRP3 4349/4885LMNA 3363/4885ALDH1A1 1907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.