SCHEMBL15071493

SCHEMBL15071493

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nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ RNASEL Q05823 1/20 0.37
▸ ADSS2 P30520 1/20 0.31
▸ TK1 P04183 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14946191 1.00 RNASEL (0.37) RNASELADSS2TK1
SCHEMBL14928703 1.00 RNASEL (0.37) RNASELADSS2TK1
SCHEMBL14945963 1.00 RNASEL (0.37) RNASELADSS2TK1
SCHEMBL15249232 1.00 RNASEL (0.37) RNASELADSS2TK1
SCHEMBL17263511 1.00 RNASEL (0.37) RNASELADSS2TK1
SCHEMBL20126561 1.00 RNASEL (0.37) RNASELADSS2TK1
SCHEMBL15248821 1.00 RNASEL (0.37) RNASELADSS2TK1
SCHEMBL14946187 0.90 P2RY2 (0.37) RNASEL
SCHEMBL15071506 0.81 PGD (0.31) TK1
SCHEMBL15248823 0.81 PGD (0.31) TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130165504-A1 METHODS OF INCREASING THE VIABILITY OR LONGEVITY OF AN ORGAN OR ORGAN EXPLANT modeRNA Therapeutics (US) 2013-06-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130165504-A1 METHODS OF INCREASING THE VIABILITY OR LONGEVITY OF AN ORGAN OR ORGAN EXPLANT RNGTT, L3MBTL3, RNASE1 RNASEL 47/4885ADSS2 1154/4885TK1 1102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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