SCHEMBL15071495

SCHEMBL15071495

Cn1c(N)nc2c(ncn2C2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)c1=O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA5A P35218 1/20 0.67
P2RY1 P47900 4/20 0.65
TAS1R3 Q7RTX0 3/20 0.65
TAS1R1 Q7RTX1 3/20 0.65
P2RY11 Q96G91 3/20 0.65
DNPH1 O43598 1/20 0.65
PRKAB2 O43741 1/20 0.65
TRPM2 O94759 1/20 0.65
LDHA P00338 1/20 0.65
ADRB2 P07550 1/20 0.65
FBP1 P09467 1/20 0.65
SRC P12931 1/20 0.65
ADORA1 P30542 1/20 0.65
P2RY2 P41231 1/20 0.65
PRKAG1 P54619 1/20 0.65
PRKAA2 P54646 1/20 0.65
PDE4D Q08499 1/20 0.65
KCNH2 Q12809 1/20 0.65
PRKAA1 Q13131 1/20 0.65
PDE3A Q14432 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL263420 1.00 CA5A (0.67) CA5AP2RY1TAS1R3TAS1R1P2RY11
SCHEMBL263421 1.00 CA5A (0.67) CA5AP2RY1TAS1R3TAS1R1P2RY11
SCHEMBL17010791 1.00 CA5A (0.67) CA5AP2RY1TAS1R3TAS1R1P2RY11
SCHEMBL309060 0.93 P2RY1 (0.71) P2RY1P2RY11SRCP2RY2SMN1; SMN2
SCHEMBL625113 0.92 P2RY1 (0.72) P2RY1P2RY11SRCP2RY2SMN1; SMN2
SCHEMBL20901220 0.92 P2RY1 (0.72) P2RY1P2RY11SRCP2RY2SMN1; SMN2
SCHEMBL14928757 0.92 P2RY1 (0.72) P2RY1P2RY11SRCP2RY2SMN1; SMN2
SCHEMBL14948858 0.92 P2RY1 (0.72) P2RY1P2RY11SRCP2RY2SMN1; SMN2
SCHEMBL19442379 0.92 P2RY1 (0.72) P2RY1P2RY11SRCP2RY2SMN1; SMN2
SCHEMBL14853693 0.92 P2RY1 (0.72) P2RY1P2RY11SRCP2RY2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130165504-A1 METHODS OF INCREASING THE VIABILITY OR LONGEVITY OF AN ORGAN OR ORGAN EXPLANT modeRNA Therapeutics (US) 2013-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130165504-A1 METHODS OF INCREASING THE VIABILITY OR LONGEVITY OF AN ORGAN OR ORGAN EXPLANT RNGTT, L3MBTL3, RNASE1 CA5A 3364/4885P2RY1 3103/4885TAS1R3 4077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.