SCHEMBL1507331

SCHEMBL1507331

ClCC(=CC=Cc1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.46
LMNA P02545 4/20 0.44
ALDH1A1 P00352 5/20 0.41
MAPK1 P28482 3/20 0.41
TRPA1 O75762 2/20 0.41
ALOX5 P09917 1/20 0.41
KDM4E B2RXH2 2/20 0.40
MAPT P10636 2/20 0.40
RECQL P46063 2/20 0.40
PLIN1 O60240 1/20 0.40
BCHE P06276 1/20 0.40
TNFRSF1A P19438 1/20 0.40
ACHE P22303 1/20 0.40
PLIN5 Q00G26 1/20 0.40
CYP1B1 Q16678 1/20 0.40
ABHD5 Q8WTS1 1/20 0.40
GRIK1 P39086 1/20 0.40
GSK3B P49841 1/20 0.39
HIF1A Q16665 1/20 0.39
MCL1 Q07820 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9437054 0.85 LMNA (0.37) MAOBLMNAALDH1A1MAPK1TRPA1
SCHEMBL5101844 0.81 LMNA (0.48) MAOBLMNAALDH1A1MAPK1TRPA1
SCHEMBL22192129 0.81 LMNA (0.48) MAOBLMNAALDH1A1MAPK1TRPA1
SCHEMBL369667 0.77 LMNA (0.44) MAOBLMNAALDH1A1MAPK1TRPA1
SCHEMBL9870798 0.76 MTNR1A (0.51) ALDH1A1MAPK1TRPA1GSK3BHIF1A
SCHEMBL9870801 0.76 MTNR1A (0.51) ALDH1A1MAPK1TRPA1GSK3BHIF1A
SCHEMBL2380962 0.76 KDM4E (0.48) MAOBLMNAALDH1A1KDM4EMAPT
SCHEMBL28023700 0.76 LMNA (0.43) MAOBLMNAALDH1A1MAPK1TRPA1
SCHEMBL9741942 0.75 ALDH1A1 (0.37) MAOBALDH1A1MAPK1TRPA1KDM4E
SCHEMBL686735 0.75 LMNA (0.40) MAOBLMNAALDH1A1MAPK1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997031034-A1 METHOD FOR REDUCING CRAZING IN A PLASTICS MATERIAL COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1997-08-28 WO claimed
JP-9302101-A None JP disclosed
US-8974984-B2 Power generation system using an alkaline fuel cell and fuel gas for alkaline fuel cells used in the system TOKUYAMA CORPORATION (JP) 2015-03-10 US disclosed
EP-2224523-B1 SOLID POLYMER ELECTROLYTE FUEL CELL MEMBRANE TOKUYAMA CORP (JP) 2014-07-23 EP disclosed
US-8440366-B2 Solid polymer electrolyte fuel cell membrane with anion exchange membrane TOKUYAMA CORPORATION (JP) 2013-05-14 US disclosed
EP-2461411-A9 POWER GENERATION SYSTEM UTILIZING ALKALINE FUEL CELL, AND FUEL GAS FOR ALKALINE FUEL CELL FOR USE IN THE SYSTEM Tokuyama Corporation (JP) 2012-08-15 EP disclosed
EP-2461411-A1 POWER GENERATION SYSTEM UTILIZING ALKALINE FUEL CELL, AND FUEL GAS FOR ALKALINE FUEL CELL FOR USE IN THE SYSTEM Tokuyama Corporation (JP) 2012-06-06 EP disclosed
US-20120122006-A1 Power Generation System Using an Alkaline Fuel Cell and Fuel Gas for Alkaline Fuel Cells Used in the System TOKUYAMA CORPORATION (JP) 2012-05-17 US disclosed
US-20110104590-A1 Method for Producing Ion Conductivity Providing Agent for Catalyst Electrode Layer in Anion-Exchange Membrane Type Fuel Cell TOKUYAMA CORPORATION (JP) 2011-05-05 US disclosed
EP-2296210-A1 METHOD FOR PRODUCING ION CONDUCTIVITY-IMPARTING AGENT FOR CATALYST ELECTRODE LAYER OF ANION-EXCHANGE MEMBRANE FUEL CELL Tokuyama Corporation (JP) 2011-03-16 EP disclosed
EP-0709402-B1 Glycosylated latex or mineral oxide particle, process for the preparation of such a particle and use thereof as a biological detection agent or as an affinity chromatography agent MERCK EUROLAB S A (FR) 2002-06-26 EP disclosed
WO-2000078740-A1 SOLID-SUPPORTED INITIATORS AND FUNCTIONAL POLYMERS FOR USE IN ORGANIC SYNTHESIS AND COMBINATORIAL CHEMISTRY WARNER-LAMBERT COMPANY (US) 2000-12-28 WO disclosed
EP-1044297-A2 SOLID SUPPORT MATERIALS Cambridge Drug Discovery Limited (GB) 2000-10-18 EP disclosed
WO-2000050467-A1 POLYMERS AND COPOLYMERS PREPARED OR MODIFIED BY USING COBALT COMPLEXES THE UNIVERSITY OF AKRON (US) 2000-08-31 WO disclosed
WO-1999032705-A2 SOLID SUPPORT MATERIALS CAMBRIDGE DRUG DISCOVERY LIMITED (GB) 1999-07-01 WO disclosed
JP-H09302101-A PRODUCTION OF OPTICAL ELEMENT DAINIPPON INK & CHEM INC 1997-11-25 JP disclosed
EP-0709402-A1 Latex particles of glycosylated mineral oxides, process for the preparation of such particles and use thereof as biological detecting agents of affinity chromatography agents SOCIETE PROLABO (FR) 1996-05-01 EP disclosed
US-5320708-A Dry etching method SONY CORPORATION (JP) 1994-06-14 US disclosed
US-5079093-A Two layer polymeric coating wherein layers react with each other TORAY INDUSTRIES, INC. (JP) 1992-01-07 US disclosed
EP-0389632-A1 SLIPPERY MEDICAL MATERIAL AND PROCESS FOR ITS PRODUCTION TORAY INDUSTRIES, INC. (JP) 1990-10-03 EP disclosed