Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15074813 | 0.95 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1GLAMAPTHPGD | |
| SCHEMBL30680642 | 0.92 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1GLAMAPTHPGD | |
| SCHEMBL8371903 | 0.92 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1GLAMAPTHPGD | |
| SCHEMBL10382309 | 0.88 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1GLAMAPTHPGD | |
| SCHEMBL10540535 | 0.88 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1GLAMAPTHPGD | |
| SCHEMBL16394145 | 0.84 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1GLAMAPTHPGD | |
| SCHEMBL16405440 | 0.84 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1GLAMAPTHPGD | |
| SCHEMBL9721753 | 0.83 | CA1 (0.40) | ALDH1A1L3MBTL1TDP1POLB | |
| SCHEMBL15074815 | 0.80 | L3MBTL1 (0.41) | ALDH1A1L3MBTL1GLAMAPTTDP1 | |
| SCHEMBL10702144 | 0.80 | CA1 (0.40) | ALDH1A1L3MBTL1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150025280-A1 | LIGANDS FOR RHODIUM CATALYZED REDUCTIVE CARBONYLATION OF ALCOHOLS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-01-22 | — | — | US | disclosed |
| US-20150025280-A1 | LIGANDS FOR RHODIUM CATALYZED REDUCTIVE CARBONYLATION OF ALCOHOLS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-01-22 | — | — | US | disclosed |
| WO-2013096631-A1 | LIGANDS FOR RHODIUM CATALYZED REDUCTIVE CARBONYLATION OF ALCOHOLS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150025280-A1 | LIGANDS FOR RHODIUM CATALYZED REDUCTIVE CARBONYLATION OF ALCOHOLS | ADH5, ADH1C, ADH1A | ALDH1A1 208/4885L3MBTL1 3388/4885GLA 2539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.