Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.74 |
| ▸ | HPGD | P15428 | 8/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.74 |
| ▸ | LMNA | P02545 | 7/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.74 |
| ▸ | TP53 | P04637 | 5/20 | 0.74 |
| ▸ | DRD2 | P14416 | 4/20 | 0.74 |
| ▸ | DRD3 | P35462 | 4/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.74 |
| ▸ | GMNN | O75496 | 4/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 4/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.74 |
| ▸ | DRD1 | P21728 | 3/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14161595 | 0.87 | MAPT (0.83) | MAPTMAPK1KDM4EHPGDALDH1A1 | |
| SCHEMBL15075316 | 0.87 | CYP1A2 (0.70) | MAPTMAPK1KDM4EHPGDALDH1A1 | |
| R-N-Propylnorapomorphine SCHEMBL13487203 | 0.85 | DRD2 (1.00) | MAPTMAPK1KDM4EHPGDALDH1A1 | |
| R-N-Propylnorapomorphine SCHEMBL29447877 | 0.85 | DRD2 (1.00) | MAPTMAPK1KDM4EHPGDALDH1A1 | |
| R-N-Propylnorapomorphine SCHEMBL7997518 | 0.85 | DRD2 (1.00) | MAPTMAPK1KDM4EHPGDALDH1A1 | |
| R-N-Propylnorapomorphine SCHEMBL13398114 | 0.85 | DRD2 (1.00) | MAPTMAPK1KDM4EHPGDALDH1A1 | |
| R-N-Propylnorapomorphine SCHEMBL249729 | 0.85 | DRD2 (1.00) | MAPTMAPK1KDM4EHPGDALDH1A1 | |
| Apomorphine SCHEMBL17870681 | 0.84 | KDM4E (0.91) | MAPTMAPK1KDM4EHPGDALDH1A1 | |
| Apomorphine SCHEMBL584927 | 0.83 | KDM4E (0.89) | MAPTMAPK1KDM4EHPGDALDH1A1 | |
| SCHEMBL19815875 | 0.83 | DRD2 (1.00) | MAPTMAPK1KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137489-A1 | Process for the Synthesis of Therapeutic Peptides | IPSEN MANUFACTURING IRELAND LIMITED (IE) | 2017-05-18 | — | — | US | disclosed |
| US-9475837-B2 | Process for the synthesis of therapeutic peptides | IPSEN MANUFACTURING IRELAND LIMITED (IE) | 2016-10-25 | — | — | US | disclosed |
| US-20150045534-A1 | Process for the Synthesis of Therapeutic Peptides | IPSEN MANUFACTURING IRELAND LIMITED (IE) | 2015-02-12 | — | — | US | disclosed |
| US-8822442-B2 | Somatostatin-dopamine chimeric analogs | IPSEN PHARMA S.A.S. (FR) | 2014-09-02 | — | — | US | disclosed |
| EP-1617856-B1 | SOMATOSTATIN-DOPAMINE CHIMERIC ANALOGS | IPSEN PHARMA (FR) | 2014-01-15 | — | — | EP | disclosed |
| WO-2013093639-A1 | PROCESS FOR THE SYNTHESIS OF THERAPEUTIC PEPTIDES | IPSEN MANUFACTURING IRELAND LIMITED (IE) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045534-A1 | Process for the Synthesis of Therapeutic Peptides | MAX, VIP, SFPQ | MAPT 1661/4885MAPK1 3838/4885KDM4E 3600/4885 |
| US-20170137489-A1 | Process for the Synthesis of Therapeutic Peptides | NPEPPS, DNPEP, QPCT | MAPT 1243/4885MAPK1 2864/4885KDM4E 3660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.