Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11777538 | 0.83 | TP53 (0.38) | TRPA1ATMALDH1A1POLBRECQL | |
| SCHEMBL10886083 | 0.81 | ALDH1A1 (0.40) | TRPA1ATMALDH1A1MAPTHSD17B10 | |
| SCHEMBL29407125 | 0.73 | ALDH1A1 (0.53) | TRPA1ATMALDH1A1POLBRECQL | |
| SCHEMBL23915 | 0.73 | ALDH1A1 (0.53) | TRPA1ATMALDH1A1POLBRECQL | |
| SCHEMBL15485256 | 0.73 | ALDH1A1 (0.53) | TRPA1ATMALDH1A1POLBRECQL | |
| SCHEMBL9985773 | 0.70 | MEN1 (0.34) | MAPTHSD17B10MEN1KMT2ALMNA | |
| SCHEMBL199801 | 0.69 | GABRA1 (0.42) | TRPA1ALDH1A1RECQLTDP1MAPT | |
| SCHEMBL68586 | 0.69 | TRPA1 (0.48) | TRPA1ATMALDH1A1POLBRECQL | |
| Water SCHEMBL29374093 | 0.69 | ALDH1A1 (0.48) | TRPA1ATMALDH1A1POLBRECQL | |
| SCHEMBL339799 | 0.69 | TDP2 (0.44) | TRPA1ATMALDH1A1POLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2325176-B1 | Process for the preparation of Isoxazolin-3-yl-Acylbenzenes | BASF SE (DE) | 2015-02-25 | — | — | EP | disclosed |
| EP-2298749-B1 | Process for the preparation of Thioethers | BASF SE (DE) | 2014-12-24 | — | — | EP | disclosed |
| EP-2325176-A1 | Process for the preparation of isoxazolin-3-yl-acylbenzenes | BASF SE (DE) | 2011-05-25 | — | — | EP | disclosed |
| EP-2298749-A1 | Process for the preparation of Thioethers | BASF SE (DE) | 2011-03-23 | — | — | EP | disclosed |
| EP-1852424-A2 | Method for manufacturing isoxazoline-3-yL-acyl benzoles | BASF AKTIENGESELLSCHAFT (DE) | 2007-11-07 | — | — | EP | disclosed |
| EP-1077955-B1 | METHOD FOR PRODUCING ISOXAZOLINE-3-YL-ACYL BENZENE | BASF AG (DE) | 2007-06-27 | — | — | EP | disclosed |
| EP-1077955-A1 | METHOD FOR PRODUCING ISOXAZOLINE-3-YL-ACYL BENZENE | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058509-A1 | METHOD FOR PRODUCING ISOXAZOLINE-3-YL-ACYL BENZENE | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-18 | — | — | WO | disclosed |