Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 5/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15078745 | 0.91 | PLA2G2A (0.43) | PLA2G2APLA2G10PLA2G1BPLA2G5MAPK1 | |
| SCHEMBL15078748 | 0.86 | TLR4 (0.41) | PLA2G2APLA2G10PLA2G1BPLA2G5LTB4R | |
| SCHEMBL15078764 | 0.84 | ALOX5 (0.47) | MAPK1ALOX5TP53CYP1A2CYP3A4 | |
| SCHEMBL15016887 | 0.80 | ALOX5 (0.56) | MAPK1ALOX5TP53CYP1A2CYP3A4 | |
| SCHEMBL15078742 | 0.77 | PLA2G2A (0.47) | PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL18175239 | 0.74 | ALOX5 (0.50) | MAPK1ALOX5TP53CYP1A2CYP3A4 | |
| SCHEMBL15078762 | 0.74 | ALOX5 (0.48) | MAPK1ALOX5TP53CYP1A2CYP3A4 | |
| SCHEMBL6055172 | 0.74 | LMNA (0.52) | MAPK1ALOX5TP53CYP1A2CYP3A4 | |
| SCHEMBL17805709 | 0.73 | ALOX5 (0.47) | MAPK1ALOX5TP53CYP1A2CYP3A4 | |
| SCHEMBL16451181 | 0.73 | ALOX5 (0.47) | MAPK1ALOX5TP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130165411-A1 | TRICYCLIC BORON COMPOUNDS FOR ANTIMICROBIAL THERAPY | MICURX PHARMACEUTICALS, INC. (KY) | 2013-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165411-A1 | TRICYCLIC BORON COMPOUNDS FOR ANTIMICROBIAL THERAPY | TBCA, TBCB, BTD | PLA2G2A 4879/4885PLA2G10 4874/4885PLA2G1B 4878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.