Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15016887 | 0.90 | ALOX5 (0.56) | ALOX5CYSLTR2CYSLTR1MAPK1TSHR | |
| SCHEMBL15078762 | 0.89 | ALOX5 (0.48) | ALOX5LTB4RPTGESPPARGPPARA | |
| SCHEMBL16451181 | 0.85 | ALOX5 (0.47) | ALOX5LTB4RCYSLTR2CYSLTR1MAPK1 | |
| SCHEMBL17805709 | 0.85 | ALOX5 (0.47) | ALOX5LTB4RCYSLTR2CYSLTR1MAPK1 | |
| SCHEMBL15078749 | 0.84 | PLA2G2A (0.42) | ALOX5LTB4RCYSLTR2CYSLTR1MAPK1 | |
| SCHEMBL4572157 | 0.84 | MAPK1 (0.50) | ALOX5LTB4RCYSLTR2CYSLTR1MAPK1 | |
| SCHEMBL29818894 | 0.84 | LMNA (0.45) | ALOX5CYSLTR2CYSLTR1MAPK1TSHR | |
| SCHEMBL18175239 | 0.84 | ALOX5 (0.50) | ALOX5LTB4RPTGESPPARGPPARA | |
| SCHEMBL15078760 | 0.83 | TLR4 (0.48) | ALOX5LTB4RPTGESPPARGPPARA | |
| SCHEMBL4572161 | 0.83 | ALOX5 (0.46) | ALOX5LTB4RCYSLTR2CYSLTR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130165411-A1 | TRICYCLIC BORON COMPOUNDS FOR ANTIMICROBIAL THERAPY | MICURX PHARMACEUTICALS, INC. (KY) | 2013-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165411-A1 | TRICYCLIC BORON COMPOUNDS FOR ANTIMICROBIAL THERAPY | TBCA, TBCB, BTD | ALOX5 4065/4885LTB4R 2714/4885PTGES 4621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.