SCHEMBL1507929

SCHEMBL1507929

O=C(NOC(=O)C(F)(F)F)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.43
ALDH1A1 P00352 1/20 0.37
POLB P06746 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CA3 P07451 2/20 0.32
CA5A P35218 2/20 0.32
CA5B Q9Y2D0 2/20 0.32
CA12 O43570 2/20 0.32
CA9 Q16790 2/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA7 P43166 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA1 P00915 1/20 0.31
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3906654 0.79 CA2 (0.32) CA2CA5ACA9
SCHEMBL508488 0.77 CA2 (0.31) CA2
SCHEMBL6983915 0.77 CA2 (0.31) CA2
SCHEMBL28451597 0.77 MLYCD (0.37) MEN1KMT2A
SCHEMBL507991 0.76
SCHEMBL6983918 0.75
SCHEMBL6507208 0.75 TAS2R38 (0.32)
SCHEMBL27716074 0.75 CA2 (0.40) CA2ALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL27635061 0.75 F2 (0.33) SMN1; SMN2
SCHEMBL8512564 0.75 CA2 (0.36) CA2ALDH1A1POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11444330-B2 Electrolytic solution and electrochemical device using the same NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2022-09-13 US claimed
US-20210408604-A1 ELECTROLYTIC SOLUTION AND ELECTROCHEMICAL DEVICE USING THE SAME NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2021-12-30 US claimed
EP-0116329-A1 D-Homo steroids, their preparation and pharmaceutical compositions F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1984-08-22 EP claimed
WO-2025262036-A1 METHOD OF MANUFACTURING A PHARMACEUTICAL COMPOSITION RNASSIST LTD (GB) 2025-12-26 WO disclosed
US-20250288559-A1 PREP BINDING LIGANDS POLKU THERAPEUTICS OY (FI) 2025-09-18 US disclosed
US-20250110101-A1 PER AND POLYFLUOROALKYL SUBSTANCE MEASUREMENT DEXSIL CORPORATION (US) 2025-04-03 US disclosed
EP-4514781-A1 PREP BINDING LIGANDS Polku Therapeutics OY (FI) 2025-03-05 EP disclosed
EP-3827241-B1 DISSOCIATION OF BIOLOGICAL SAMPLES GOLDSBOROUGH ANDREW SIMON (FR) 2024-03-13 EP disclosed
US-20240059860-A1 METHODS AND SYSTEMS FOR DESTRUCTION OF SYNTHETIC PER- AND POLYFLUORO COMPOUNDS CHZ TECHNOLOGIES, LLC 2024-02-22 US disclosed
US-20240027309-A1 SIMPLE FIXATION AND STABILISATION RNASSIST LTD (GB) 2024-01-25 US disclosed
WO-2023209191-A1 PREP BINDING LIGANDS UNIVERSITY OF HELSINKI (FI) 2023-11-02 WO disclosed
EP-0112481-A1 Beta-lactam compound KYOWA HAKKO KOGYO CO., LTD (JP) 1984-07-04 EP disclosed
US-4451479-A ANTIINFLAMMATORY AMERICAN CYANAMID COMPANY (US) 1984-05-29 US disclosed
US-4394386-A Fluorinated carbamate insecticides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-19 US disclosed
US-4393074-A Fluorinated carbamate insecticides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-12 US disclosed
US-4335140-A Insecticidal trifluoroethanimidothioate disulfides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-06-15 US disclosed
US-4323578-A Fluorinated carbamate insecticides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-04-06 US disclosed
US-4054604-A MICROBIOCIDES, HYPOTENSIVE AGENTS AMERICAN CYANAMID COMPANY (US) 1977-10-18 US disclosed
US-4044043-A HYPERTENSIVE AGENTS, MICROBIOCIDES AMERICAN CYANAMID COMPANY (US) 1977-08-23 US disclosed
US-3981868-A MICROBIOCIDES, HYPOTENSIVE AGENTS AMERICAN CYANAMID COMPANY (US) 1976-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240027309-A1 SIMPLE FIXATION AND STABILISATION EWSR1, FOSB, PAXBP1 CA2 2898/4885ALDH1A1 4284/4885POLB 214/4885
US-20250288559-A1 PREP BINDING LIGANDS PREP, ERAP2, CTSA CA2 1662/4885ALDH1A1 4707/4885POLB 1992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.