SCHEMBL1507948

SCHEMBL1507948

O=C(O)COS(=O)(=O)O.O=S(=O)(O)c1ccccc1

nearest known ligand 0.59

Known targets — ChEMBL curated mechanism

BTKCACNA1CCACNA1DCACNA1FCACNA1SCACNA2D1CACNA2D2DRD2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQHRH1HTR2AP2RY12

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.59
TSHR P16473 1/20 0.59
POLB P06746 2/20 0.43
CYP2D6 P10635 1/20 0.43
ALOX15 P16050 1/20 0.42
ALDH1A1 P00352 3/20 0.41
TBXA2R P21731 2/20 0.39
TBXAS1 P24557 1/20 0.39
CYP2C19 P33261 1/20 0.39
PAM P19021 1/20 0.38
LMNA P02545 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.37
MMP2 P08253 1/20 0.37
MMP7 P09237 1/20 0.37
MMP14 P50281 1/20 0.37
HSD11B1 P28845 1/20 0.37
GLA P06280 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL168709 0.79
SCHEMBL9243189 0.79 ALOX15 (0.47) SMN1; SMN2TSHRPOLBALOX15ALDH1A1
Malonic Acid SCHEMBL20594155 0.78 SMN1; SMN2 (0.73) SMN1; SMN2TSHRPOLBCYP2D6ALDH1A1
Ammonia Solution, Strong SCHEMBL11317665 0.77 TSHR (0.39) TSHRPOLBALOX15ALDH1A1
Bicarbonate SCHEMBL15282245 0.77 TSHR (0.89) SMN1; SMN2TSHRPOLBCYP2D6ALDH1A1
Methane SCHEMBL9595604 0.77 TSHR (0.39) TSHRPOLBALOX15ALDH1A1
SCHEMBL28279642 0.77 TSHR (0.39) TSHRPOLBALOX15ALDH1A1
SCHEMBL11280732 0.77 TSHR (0.39) TSHRPOLBALOX15ALDH1A1
SCHEMBL27845788 0.77 TSHR (0.39) TSHRPOLBALOX15ALDH1A1
Bicarbonate SCHEMBL28272077 0.77 TSHR (0.89) SMN1; SMN2TSHRPOLBCYP2D6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2289970-B1 Biocompatible polymers BARRITAULT DENIS (FR) 2015-05-20 EP disclosed
EP-1117695-B1 BIOCOMPATIBLE POLYMERS, COMPOSITIONS CONTAINING SAME AND THEIR USE FOR THE MANUFACTURE OF DRUGS BARRITAULT DENIS (FR) 2015-05-20 EP disclosed
EP-2289970-A1 Biocompatible polymers, their process of manufacture and compositions containing them Barritault, Denis (FR) 2011-03-02 EP disclosed