SCHEMBL15079755

SCHEMBL15079755

CC(C)c1ccc(OCC(O)c2ccccc2O)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
MAPK1 P28482 4/20 0.45
LMNA P02545 3/20 0.45
MAPT P10636 3/20 0.45
GAA P10253 1/20 0.45
HTT P42858 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.42
HIF1A Q16665 2/20 0.41
CYP1A2 P05177 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
CYP2D6 P10635 1/20 0.41
DRD1 P21728 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15079364 0.86 MEN1 (0.47) KMT2AMEN1GABRA1GABRB2MAPK1
SCHEMBL15079894 0.84 SCN4A (0.47) KMT2AMEN1MAPK1LMNAGAA
SCHEMBL15079914 0.84 TSHR (0.46) KMT2AMEN1MAPK1LMNAMAPT
SCHEMBL15079749 0.82 MAPT (0.44) KMT2AMEN1GABRA1GABRB2LMNA
SCHEMBL9854787 0.81 CYP1A2 (0.41) KMT2AMEN1LMNAMAPTGAA
SCHEMBL15079881 0.81 LTA4H (0.49) LMNAMAPTHTTSMN1; SMN2CYP2D6
SCHEMBL15079883 0.81 KDM1A (0.46) KMT2AMEN1MAPK1LMNAMAPT
SCHEMBL15079844 0.81 HTT (0.46) KMT2AMEN1LMNAMAPTGAA
SCHEMBL15079919 0.79 HTR7 (0.47) KMT2AMEN1LMNAMAPTALDH1A1
SCHEMBL15079778 0.79 ALDH1A1 (0.46) KMT2AMEN1MAPTALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2015-01-01 US disclosed
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2015-01-01 US disclosed
WO-2013093320-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2013-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS ARG1, TYR, NOS1 KMT2A 1478/4885MEN1 4010/4885GABRA1 4118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.