SCHEMBL15079889

SCHEMBL15079889

Oc1ccccc1CCOc1ccc(OC(F)(F)F)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.58
MAPT P10636 1/20 0.58
HTT P42858 1/20 0.58
RAB9A P51151 1/20 0.58
KMT2A Q03164 1/20 0.58
CYP4F2 P78329 1/20 0.46
CYP4A11 Q02928 1/20 0.46
FFAR4 Q5NUL3 2/20 0.43
FFAR1 O14842 1/20 0.43
MAOB P27338 1/20 0.43
AOC3 Q16853 1/20 0.43
TRPV1 Q8NER1 3/20 0.43
TYR P14679 1/20 0.42
SLC6A4 P31645 2/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A3 Q01959 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
PPARG P37231 1/20 0.40
KCNA5 P22460 1/20 0.40
GRIN2B Q13224 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9854722 0.83 MPO (0.51) MAPTRAB9ACYP4F2CYP4A11TYR
SCHEMBL8470716 0.83 MEN1 (0.60) MEN1MAPTHTTRAB9AKMT2A
SCHEMBL16368719 0.82 CYP4F2 (0.51) CYP4F2CYP4A11TYRSLC6A2SLC6A3
SCHEMBL9854724 0.81 KCNA3 (0.52) RAB9ACYP4F2CYP4A11TYRTAAR1
SCHEMBL15079368 0.79 CYP4F2 (0.47) MEN1MAPTKMT2ACYP4F2CYP4A11
SCHEMBL15079888 0.79 PTGER4 (0.51) CYP4F2CYP4A11TAAR1MMP3
SCHEMBL15079379 0.79 RAB9A (0.59) MAPTRAB9AKMT2ACYP4F2CYP4A11
SCHEMBL15079867 0.79 MEN1 (0.51) MEN1MAPTKMT2ACYP4F2CYP4A11
SCHEMBL16368718 0.79 CYP4F2 (0.49) MEN1RAB9AKMT2ACYP4F2CYP4A11
SCHEMBL15079427 0.79 LTA4H (0.53) CYP4F2CYP4A11TAAR1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2015-01-01 US disclosed
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2015-01-01 US disclosed
WO-2013093320-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2013-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS ARG1, TYR, NOS1 MEN1 4010/4885MAPT 3297/4885HTT 324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.