SCHEMBL1508068

SCHEMBL1508068

NCC(=O)OC(=O)[C@@H]1CCCN1.O=C(O)[C@H]1NCCC1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
BLM P54132 1/20 0.39
ARG1 P05089 5/20 0.36
SLC1A2 P43004 1/20 0.34
NOS2 P35228 2/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
ARG2 P78540 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
THRB P10828 1/20 0.31
ALOX15 P16050 1/20 0.31
CYP2C19 P33261 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIA1 P42261 1/20 0.31
GRIA2 P42262 1/20 0.31
GRIA3 P42263 1/20 0.31
GRIA4 P48058 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3091834 0.86 SLC1A2 (0.40) MEN1KMT2ABLMARG1SLC1A2
Proline SCHEMBL4398037 0.85 MEN1 (0.44) MEN1KMT2ABLMARG1SLC1A2
Proline SCHEMBL1196246 0.85 MEN1 (0.44) MEN1KMT2ABLMARG1SLC1A2
Proline SCHEMBL28467818 0.85 MEN1 (0.44) MEN1KMT2ABLMARG1SLC1A2
SCHEMBL302682 0.85 NOS2 (0.41) NOS2NOS3NOS1
Proline SCHEMBL1820143 0.82 MEN1 (0.52) MEN1KMT2ABLMARG1SLC1A2
Proline SCHEMBL162687 0.82 MEN1 (0.52) MEN1KMT2ABLMARG1SLC1A2
SCHEMBL4398036 0.80 MEN1 (0.35) MEN1KMT2ABLMARG1SLC1A2
SCHEMBL13519375 0.77 NOS2 (0.35) ARG1NOS2NOS3NOS1ARG2
SCHEMBL6534977 0.76 SLC1A2 (0.33) MEN1KMT2ABLMARG1SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115317589-A Prolyl hydroxylase inhibitors and uses thereof 中国海洋大学 2022-11-11 CN claimed
WO-2024077483-A1 OLIGOPEPTIDE AND USE AND COMPOSITION THEREOF 佛教慈济医疗财团法人 2024-04-18 WO disclosed
CN-117736264-A Oligopeptide and application and composition thereof 佛教慈济医疗财团法人 2024-03-22 CN disclosed
EP-3687564-B1 RECOMBINANT COLLAGEN AND ELASTIN MOLECULES AND USES THEREOF GELTOR INC (US) 2023-11-15 EP disclosed
WO-2023194333-A1 RECOMBINANT SPIDER SILK-REINFORCED COLLAGEN PROTEINS PRODUCED IN PLANTS AND THE USE THEREOF SWIFTPHARMA BV (BE) 2023-10-12 WO disclosed
CN-116178525-A Recombinant collagen and elastin molecules and uses thereof 格尔托公司 2023-05-30 CN disclosed
CN-110128502-B Amphiphilic polypeptide molecule with temperature-sensitive aggregation-induced emission characteristic and preparation method thereof 上海大学 2023-05-16 CN disclosed
US-20230104758-A1 COMPOUNDS AND METHODS FOR AMINE OXIDASE IMAGING ETH ZURICH (CH) 2023-04-06 US disclosed
CN-111417404-B Recombinant collagen and elastin molecules and uses thereof 格尔托公司 2023-03-10 CN disclosed
CN-115317589-A Prolyl hydroxylase inhibitors and uses thereof 中国海洋大学 2022-11-11 CN disclosed
US-8575311-B2 Collagen peptide conjugates and uses therefor PURDUE RESEARCH FOUNDATION (US) 2013-11-05 US disclosed
WO-2012112767-A2 COLLAGEN-TARGETED NANOPARTICLES PURDUE RESEARCH FOUNDATION (US) 2012-08-23 WO disclosed
US-20110081324-A1 COLLAGEN PEPTIDE CONJUGATES AND USES THEREFOR PURDUE RESEARCH FOUNDATION (US) 2011-04-07 US disclosed
EP-2300033-A1 COLLAGEN PEPTIDE CONJUGATES AND USES THEREFOR Purdue Research Foundation (US) 2011-03-30 EP disclosed
WO-2009140573-A1 COLLAGEN PEPTIDE CONJUGATES AND USES THEREFOR PURDUE RESEARCH FOUNDATION (US) 2009-11-19 WO disclosed
EP-1996013-A2 METHODS AND COMPOSITIONS FOR ORGAN AND TISSUE FUNCTIONALITY Dask Technologies, LLC (US) 2008-12-03 EP disclosed
EP-1940424-A2 COMPOSITIONS AND METHODS FOR THE AUGMENTATION AND REPAIR OF DEFECTS IN TISSUE Dask Technologies, LLC (US) 2008-07-09 EP disclosed
WO-2007035843-A2 METHODS AND COMPOSITIONS FOR ORGAN AND TISSUE FUNCTIONALITY DASK TECHNOLOGIES, LLC (US) 2007-03-29 WO disclosed
WO-2007035363-A2 COMPOSITIONS AND METHODS FOR THE AUGMENTATION AND REPAIR OF DEFECTS IN TISSUE DASK TECHNOLOGIES, LLC (US) 2007-03-29 WO disclosed
US-20070065415-A1 Compositions and methods for the augmentation and repair of defects in tissue DASK TECHNOLOGIES, LLC 2007-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230104758-A1 COMPOUNDS AND METHODS FOR AMINE OXIDASE IMAGING DAO, LOX, AOC2 MEN1 1331/4885KMT2A 773/4885BLM 2191/4885
US-20110081324-A1 COLLAGEN PEPTIDE CONJUGATES AND USES THEREFOR COL14A1, COL1A1, COL2A1 MEN1 3734/4885KMT2A 4319/4885BLM 1853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.