SCHEMBL15085539

SCHEMBL15085539

CNC(=O)c1cc(C#N)cc(C)c1NC(=O)C1CC(c2cccnc2S(=O)(=O)O)=NN1c1ncccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 5/20 0.35
MTOR P42345 1/20 0.31
RPTOR Q8N122 1/20 0.31
MLST8 Q9BVC4 1/20 0.31
GRM4 Q14833 1/20 0.30
TYK2 P29597 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15085588 0.92 MALT1 (0.39) MALT1GRM4
SCHEMBL15085554 0.89 MALT1 (0.35) MALT1MTORRPTORMLST8GRM4
SCHEMBL15085532 0.88 MALT1 (0.32) MALT1
SCHEMBL15085541 0.88 MALT1 (0.36) MALT1MTORRPTORMLST8TYK2
SCHEMBL15085560 0.87 SMN1; SMN2 (0.32) MALT1KMT2A
SCHEMBL9290062 0.86 MALT1 (0.40) MALT1TYK2KMT2A
SCHEMBL1148490 0.85 MALT1 (0.40) MALT1GRM4TYK2KMT2A
SCHEMBL902832 0.84 MALT1 (0.39) MALT1GRM4TYK2KMT2A
SCHEMBL15085579 0.84 GRM5 (0.35) MALT1
SCHEMBL15085649 0.82 P2RX7 (0.38) MALT1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481744-B2 Process for producing anthranilamide compound ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-07-09 US disclosed