SCHEMBL15085995

SCHEMBL15085995

CC1C(C)C2OC1C1C(=O)N(C3CCCCC3)C(=O)C21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.53
SMN1; SMN2 Q16637 4/20 0.53
CYP2C9 P11712 3/20 0.53
CYP2C19 P33261 3/20 0.53
CYP3A4 P08684 1/20 0.53
KMT2A Q03164 1/20 0.53
NPSR1 Q6W5P4 1/20 0.45
LMNA P02545 3/20 0.44
POLB P06746 2/20 0.44
GAA P10253 2/20 0.44
MAPT P10636 3/20 0.42
THRB P10828 2/20 0.42
TP53 P04637 1/20 0.42
HIF1A Q16665 1/20 0.42
ADRA2A P08913 1/20 0.37
NISCH Q9Y2I1 1/20 0.37
ADCY2 Q08462 2/20 0.37
ALOX15 P16050 1/20 0.36
HTT P42858 1/20 0.36
CREBBP Q92793 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15086031 0.75 NPSR1 (0.43) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL9463318 0.75 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL7603402 0.74 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL17469331 0.73 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL828074 0.73 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL10014722 0.69 KMT2A (0.61) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL15744622 0.67 LMNA (0.53) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL31372407 0.67 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL20464796 0.67 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL31372514 0.67 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9212241-B2 Optical film and display device including same SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-15 US disclosed
US-20130172503-A1 OPTICAL FILM AND DISPLAY DEVICE INCLUDING SAME CHEIL INDUSTRIES INC. (KR) 2013-07-04 US disclosed