Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ADCY2 | Q08462 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL828074 | 1.00 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17532437 | 0.85 | ATM (0.46) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31372407 | 0.76 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL521622 | 0.76 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31372514 | 0.76 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20464796 | 0.76 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2756761 | 0.73 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15085995 | 0.73 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13135498 | 0.71 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10014722 | 0.71 | KMT2A (0.61) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160022833-A1 | SOLID PHASE TGASE-MEDIATED CONJUGATION OF ANTIBODIES | ARARIS BIOTECH LTD (CH) | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022833-A1 | SOLID PHASE TGASE-MEDIATED CONJUGATION OF ANTIBODIES | TGM2, TGM3, TGM6 | ALDH1A1 1768/4885SMN1; SMN2 2458/4885CYP3A4 202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.