Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 7/20 | 0.59 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 5/20 | 0.54 |
| ▸ | CA2 | P00918 | 5/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16926675 | 0.94 | USP2 (0.56) | USP2L3MBTL1CA9P2RY6CA1 | |
| SCHEMBL10153957 | 0.90 | USP2 (0.66) | USP2L3MBTL1CA9CA1CA2 | |
| SCHEMBL3289756 | 0.90 | FOLH1 (0.62) | USP2L3MBTL1CA9CA1CA2 | |
| SCHEMBL13763752 | 0.89 | P2RY6 (0.53) | USP2L3MBTL1CA9P2RY6CA1 | |
| SCHEMBL23258882 | 0.88 | USP2 (0.63) | USP2L3MBTL1CA9CA1CA2 | |
| SCHEMBL16153102 | 0.87 | USP2 (0.64) | USP2L3MBTL1CA9CA1CA2 | |
| SCHEMBL10138306 | 0.87 | USP2 (0.69) | USP2L3MBTL1CA9CA1CA2 | |
| SCHEMBL13656547 | 0.87 | USP2 (0.72) | USP2L3MBTL1CA9CA1CA2 | |
| SCHEMBL15087770 | 0.86 | USP2 (0.61) | USP2L3MBTL1CA9CA1CA2 | |
| SCHEMBL15143443 | 0.86 | USP2 (0.63) | USP2L3MBTL1CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180064829-A1 | FLUORESCENT BISPHOSPHONATE ANALOGS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2018-03-08 | — | — | US | disclosed |
| EP-3278107-A1 | FLUORESCENT BISPHOSPHONATE ANALOGS | University of Southern California (US) | 2018-02-07 | — | — | EP | disclosed |
| WO-2016161407-A1 | FLUORESCENT BISPHOSPHONATE ANALOGS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2016-10-06 | — | — | WO | disclosed |
| EP-2256126-B1 | New labelling strategies for the sensitive detection of analytes | BASECLICK GMBH (DE) | 2015-07-01 | — | — | EP | disclosed |
| US-8242058-B2 | Reagents and methods for appending functional groups to proteins | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-08-14 | — | — | US | disclosed |
| US-8242058-B2 | Reagents and methods for appending functional groups to proteins | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-08-14 | — | — | US | disclosed |
| US-8129315-B2 | Labelling strategies for the sensitive detection of analytes | BASECLICK GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-20080020942-A1 | Reagents and Methods for Appending Functional Groups to Proteins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-01-24 | — | — | US | disclosed |
| US-20080020942-A1 | Reagents and Methods for Appending Functional Groups to Proteins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180064829-A1 | FLUORESCENT BISPHOSPHONATE ANALOGS | PPIP5K2, PHPT1, PTH1R | USP2 4869/4885L3MBTL1 3438/4885CA9 1148/4885 |
| US-20080020942-A1 | Reagents and Methods for Appending Functional Groups to Proteins | PTMS, MTPN, FGB | USP2 1618/4885L3MBTL1 426/4885CA9 4576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.