SCHEMBL1508799

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20540210	0.81	S1PR1 (0.42)	POLLNR3C2CYP11B1CYP11B2S1PR1
	SCHEMBL23948898	0.81	S1PR1 (0.42)	POLLNR3C2CYP11B1CYP11B2S1PR1
	SCHEMBL9534010	0.79	ESR1 (0.51)	HTR1A
	SCHEMBL13518633	0.79	ESR1 (0.51)	HTR1A
	SCHEMBL1746541	0.78	OPRL1 (0.51)	OPRL1KCNH2POLLOPRM1TRPV1
	SCHEMBL4641247	0.78	GID4 (0.45)	KCNH2POLLOPRM1NR3C2KMT2A
	SCHEMBL11110438	0.78	HTR2C (0.45)	OPRL1NOTUMPOLLOPRM1NR3C2
	SCHEMBL9455904	0.78	POLL (0.39)	OPRL1KCNH2POLLNR3C2KMT2A
	SCHEMBL1508536	0.78	OPRL1 (0.51)	OPRL1KCNH2POLLOPRM1TRPV1
	SCHEMBL1508379	0.78	HTR2C (0.45)	OPRL1NOTUMPOLLOPRM1NR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.