SCHEMBL15095660

SCHEMBL15095660

N#CC(C#N)=C1c2cc(-c3ccc(OC(F)(F)F)cc3)ccc2-c2cc3c(cc21)-c1ccc(-c2ccc(OC(F)(F)F)cc2)cc1C3=C(C#N)C#N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.40
ALDH1A1 P00352 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
BLM P54132 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HIF1A Q16665 1/20 0.40
HSD17B10 Q99714 1/20 0.40
EPAS1 Q99814 1/20 0.40
PKM P14618 2/20 0.38
GAA P10253 2/20 0.38
AURKA O14965 1/20 0.38
TPX2 Q9ULW0 1/20 0.38
SCN5A Q14524 4/20 0.38
KIF11 P52732 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12198595 1.00 MAPT (0.40) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL12149384 0.97 MAPT (0.38) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL20329562 0.94 TRPV1 (0.38) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL12198209 0.94 GPR3 (0.40) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL17196294 0.94 GPR3 (0.40) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL20930806 0.89 ALDH1A1 (0.40) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL12149396 0.89 AKR1C2 (0.38) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL12148955 0.88 GPR3 (0.44) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL15095662 0.88 ADORA1 (0.42) MAPTALDH1A1PKMGAAHRH3
SCHEMBL21917690 0.86 ALDH1A1 (0.38) MAPTALDH1A1MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230263001-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-08-17 US disclosed
US-20230123637-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-04-20 US disclosed
US-11575087-B1 Organic electroluminescence device, light emitting device, organic electroluminescence display device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-02-07 US disclosed
US-20230036664-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, LIGHT EMITTING DEVICE, ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-02 US disclosed
US-20210328156-A1 MIXTURE, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO.,LTD. (JP) 2021-10-21 US disclosed
US-11069861-B2 Mixture, organic electroluminescence device and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2021-07-20 US disclosed
US-10941144-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2021-03-09 US disclosed
US-20210043850-A1 MIXTURE, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO.,LTD. (JP) 2021-02-11 US disclosed
US-10573823-B2 Organic electroluminescent device JOLED INC (JP) 2020-02-25 US disclosed
US-10424740-B2 Compound, material for organic electroluminescence devices, organic electroluminescence device, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-09-24 US disclosed
EP-2833429-B1 ORGANIC ELECTROLUMINESCENCE ELEMENT JOLED INC (JP) 2019-09-18 EP disclosed
US-10411212-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2019-09-10 US disclosed
US-20190088879-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICES, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2019-03-21 US disclosed
US-20180179206-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD., (JP) 2018-06-28 US disclosed
US-9978975-B2 Organic electroluminescence device JOLED INC (JP) 2018-05-22 US disclosed
US-20150303380-A1 ORGANIC ELECTROLUMINESCENT DEVICE MAGNOLIA BLUE CORPORATION (JP) 2015-10-22 US disclosed
EP-2833700-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Sony Corporation (JP) 2015-02-04 EP disclosed
EP-2833429-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Sony Corporation (JP) 2015-02-04 EP disclosed
US-20140246663-A1 ORGANIC ELECTROLUMINESCENT ELEMENT JDI DESIGN AND DEVELOPMENT G.K. (JP) 2014-09-04 US disclosed
US-8481177-B2 Material for organic electroluminescence device and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2013-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10411212-B2 Organic electroluminescent element L1CAM, NES, EML4 MAPT 1534/4885ALDH1A1 215/4885MEN1 1048/4885
US-20180179206-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE L1CAM, ESR1, CHRM1 MAPT 1871/4885ALDH1A1 83/4885MEN1 903/4885
US-20190088879-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICES, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE PIEZO1, LEF1, L1CAM MAPT 2451/4885ALDH1A1 404/4885MEN1 633/4885
US-10424740-B2 Compound, material for organic electroluminescence devices, organic electroluminescence device, and electronic device PIEZO1, LEF1, L1CAM MAPT 2451/4885ALDH1A1 404/4885MEN1 633/4885
US-10941144-B2 Organic electroluminescence device and electronic device L1CAM, ESR1, CHRM1 MAPT 1871/4885ALDH1A1 83/4885MEN1 903/4885
US-10573823-B2 Organic electroluminescent device L1CAM, NES, EML4 MAPT 1337/4885ALDH1A1 177/4885MEN1 967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.