Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.78 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.78 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dinitro Cresol SCHEMBL1716451 | 0.92 | GPR35 (0.93) | ALDH1A1GPR35MAPTHPGDKDM4E | |
| Dinitro Cresol SCHEMBL9005468 | 0.91 | GPR35 (0.78) | ALDH1A1GPR35MAPTHPGDKDM4E | |
| Dinitro Cresol SCHEMBL1509581 | 0.91 | GPR35 (0.78) | ALDH1A1GPR35MAPTHPGDKDM4E | |
| Dinitro Cresol SCHEMBL3976321 | 0.91 | GPR35 (0.78) | ALDH1A1GPR35MAPTHPGDKDM4E | |
| Dinitro Cresol SCHEMBL2549698 | 0.90 | GPR35 (0.89) | ALDH1A1GPR35MAPTHPGDKDM4E | |
| Dinitro Cresol SCHEMBL6859521 | 0.90 | GPR35 (0.96) | ALDH1A1GPR35MAPTHPGDKDM4E | |
| Dinitro Cresol SCHEMBL9221013 | 0.89 | ALDH1A1 (0.81) | ALDH1A1GPR35MAPTHPGDKDM4E | |
| Dinitro Cresol SCHEMBL4735684 | 0.89 | GPR35 (0.81) | ALDH1A1GPR35MAPTHPGDKDM4E | |
| Trinitrophenol SCHEMBL27538937 | 0.89 | CRHBP (0.62) | ALDH1A1GPR35MAPTHPGDKDM4E | |
| Dinitro Cresol SCHEMBL29430312 | 0.88 | GPR35 (1.00) | ALDH1A1GPR35MAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107106683-A | Molecular construct comprising targeting and effector components | 中央研究院 | 2017-08-29 | — | — | CN | claimed |
| US-20110280890-A1 | PRODRUGS OF CC-1065 ANALOGS | IMMUNOGEN, INC. (US) | 2011-11-17 | — | — | US | claimed |
| US-8012978-B2 | Prodrugs of CC-A1065 analogs | IMMUNOGEN, INC. (US) | 2011-09-06 | — | — | US | claimed |
| WO-2009085576-A2 | POSITIVE CONTROL CELL PELLETS FOR IMMUNOHISTOCHEMISTRY AND METHODS OF USE THEREOF | SPRING BIOSCIENCE CORPORATION (US) | 2009-07-09 | — | — | WO | claimed |
| WO-2009085573-A2 | QUALITY CONTROL CELL DEVICE FOR IMMUNOHISTOCHEMISTRY ASSAY AND METHODS OF USE THEREOF | SPRING BIOSCIENCE CORPORATION (US) | 2009-07-09 | — | — | WO | claimed |
| US-20090028821-A1 | PRODRUGS OF CC-A1065 ANALOGS | SANOFI-AVENTIS (FR) | 2009-01-29 | — | — | US | claimed |
| EP-1993999-A1 | IMPROVED PRODRUGS OF CC-1065 ANALOGS | Sanofi-Aventis (FR) | 2008-11-26 | — | — | EP | claimed |
| WO-2007102069-A1 | IMPROVED PRODRUGS OF CC-1065 ANALOGS | SANOFI-AVENTIS (FR) | 2007-09-13 | — | — | WO | claimed |
| EP-1832577-A1 | Improved prodrugs of CC-1065 analogs | Sanofi-Aventis (FR) | 2007-09-12 | — | — | EP | claimed |
| US-4893614-A | Apparatus for disintegrating a calculus by an underwater shock wave from outside the human body | YACHIYODA SANGYO CO. LTD. (JP) | 1990-01-16 | — | — | US | claimed |
| US-4322466-A | Sheet printed with invisible inks | LOCKLEY SERVICES PTY. LTD. (AU) | 1982-03-30 | — | — | US | claimed |
| CN-111278449-B | Method for treating and/or preventing graft versus host disease and/or diffuse alveolar hemorrhage and/or venous occlusive disease associated with hematopoietic stem cell transplantation | 奥默罗斯公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-118634322-A | Methods for treating and/or preventing venous occlusive disease | 奥默罗斯公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-115594555-A | Environment-friendly high-temperature-resistant ignition agent | 西安庆华民用爆破器材股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| US-11542224-B2 | Synthesis of and compositions containing diaminoacetals and diaminoketals | ADITYA BIRLA CHEMICALS (USA), INC. (US) | 2023-01-03 | — | — | US | disclosed |
| US-4477593-A | Sheet printed with invisible inks, developers and erasure compounds _for invisible inks | LOCKLEY SERVICES PTY. LTD. (AU) | 1984-10-16 | — | — | US | disclosed |
| US-4347148-A | Full and lubricant compositions containing nitro phenols | THE LUBRIZOL CORPORATION (US) | 1982-08-31 | — | — | US | disclosed |
| US-4322466-A | Sheet printed with invisible inks | LOCKLEY SERVICES PTY. LTD. (AU) | 1982-03-30 | — | — | US | disclosed |
| US-4231757-A | OIL ADDITIVES; DETERGENTS; ANTISLUDGE AGENTS | THE LUBRIZOL CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |
| US-4197198-A | Treatment of nitrated phenol containing effluent streams | COSDEN TECHNOLOGY, INC. (US) | 1980-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110280890-A1 | PRODRUGS OF CC-1065 ANALOGS | CASP5, SENP5, CWC15 | ALDH1A1 2278/4885GPR35 844/4885MAPT 4463/4885 |
| US-11542224-B2 | Synthesis of and compositions containing diaminoacetals and diaminoketals | SRM, AOC1, SAT1 | ALDH1A1 914/4885GPR35 3109/4885MAPT 648/4885 |
| US-20090028821-A1 | PRODRUGS OF CC-A1065 ANALOGS | PDIA5, CA6, STS | ALDH1A1 971/4885GPR35 1846/4885MAPT 4480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.