Dinitro Cresol

Dinitro Cresol

SCHEMBL3976321

Cc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 6/20 0.78
ALDH1A1 P00352 5/20 0.78
CRHBP P24387 1/20 0.63
CRHR2 Q13324 1/20 0.63
MAPT P10636 6/20 0.53
HPGD P15428 4/20 0.53
KDM4E B2RXH2 4/20 0.53
KMT2A Q03164 4/20 0.53
TDP1 Q9NUW8 4/20 0.53
HSD17B10 Q99714 3/20 0.53
MEN1 O00255 3/20 0.53
MAPK1 P28482 3/20 0.53
ALOX15 P16050 2/20 0.53
ALOX12 P18054 2/20 0.53
TTR P02766 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2C9 P11712 1/20 0.53
RECQL P46063 1/20 0.53
PMP22 Q01453 1/20 0.53
HIF1A Q16665 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dinitro Cresol SCHEMBL1716451 0.92 GPR35 (0.93) GPR35ALDH1A1CRHBPCRHR2MAPT
Dinitro Cresol SCHEMBL892354 0.91 ALDH1A1 (0.78) GPR35ALDH1A1CRHBPCRHR2MAPT
Dinitro Cresol SCHEMBL1509581 0.91 GPR35 (0.78) GPR35ALDH1A1CRHBPCRHR2MAPT
Dinitro Cresol SCHEMBL2549698 0.90 GPR35 (0.89) GPR35ALDH1A1CRHBPCRHR2MAPT
Dinitro Cresol SCHEMBL6859521 0.90 GPR35 (0.96) GPR35ALDH1A1CRHBPCRHR2MAPT
Dinitro Cresol SCHEMBL9221013 0.89 ALDH1A1 (0.81) GPR35ALDH1A1CRHBPCRHR2MAPT
Dinitro Cresol SCHEMBL4735684 0.89 GPR35 (0.81) GPR35ALDH1A1CRHBPCRHR2MAPT
Trinitrophenol SCHEMBL27955220 0.89 CRHBP (0.79) GPR35ALDH1A1CRHBPCRHR2MAPT
Dinitro Cresol SCHEMBL8873755 0.88 GPR35 (1.00) GPR35ALDH1A1MAPTHPGDKDM4E
Dinitro Cresol SCHEMBL29430312 0.88 GPR35 (1.00) GPR35ALDH1A1MAPTHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106631726-A Synthetic method for optically pure double-helix oligomeric tetra-benzocyclooctene substances 香港中文大学深圳研究院 2017-05-10 CN claimed
EP-1727781-B1 PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL COUNCIL SCIENT IND RES (IN) 2009-05-06 EP claimed
CN-100456398-C Electrolyte for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORP (JP) 2009-01-28 CN claimed
EP-1727781-A1 PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL Council of Scientific and Industrial Research (IN) 2006-12-06 EP claimed
WO-2005063679-A1 PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2005-07-14 WO claimed
US-6835854-B1 Oxidation of 3,3'-dichloro 4,4'-diaminobiphenyl (DCB), ammonolysis of the resulting 3,3'-dichloro-4,4'-dinitrobiphenyl (DCDNB) and reduction of 3,3'-diamino-4,4'-dinitrobiphenyl and treating with an alkali COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-12-28 US claimed
CN-1529892-A Electrolyte for driving electrolytic capacitor and electrolytic capacitor 如碧空株式会社 2004-09-15 CN claimed
US-5275903-A Toners with liquid crystalline resins, colors and plasticizing XEROX CORPORATION (US) 1994-01-04 US claimed
CN-109721497-A The new synthetic method of one kind 2,4- dinitro biphenyl 于鹏 2019-05-07 CN disclosed
CN-103635575-B For measuring method, composition and the kit of human immunodeficiency virus (HIV) 盖立复治疗公司 2019-03-01 CN disclosed
CN-108863802-A A kind of preparation method of -4,4 '-dinitro biphenyl of 2,2 '-bis trifluoromethyl 天津市众泰化工科技有限公司 2018-11-23 CN disclosed
CN-105541637-B A kind of preparation method of 2,2 '-bis trifluoromethyl -4,4 '-benzidine 衡水均凯化工有限公司 2018-06-26 CN disclosed
CN-103137866-B Transistor, the manufacture method of transistor, display device and electronic equipment 索尼公司 2018-02-02 CN disclosed
CN-103151460-B Transistor, display device and electronic equipment 索尼公司 2017-12-22 CN disclosed
WO-2005063679-A1 PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2005-07-14 WO disclosed
US-6835854-B1 Oxidation of 3,3'-dichloro 4,4'-diaminobiphenyl (DCB), ammonolysis of the resulting 3,3'-dichloro-4,4'-dinitrobiphenyl (DCDNB) and reduction of 3,3'-diamino-4,4'-dinitrobiphenyl and treating with an alkali COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-12-28 US disclosed
CN-1529892-A Electrolyte for driving electrolytic capacitor and electrolytic capacitor 如碧空株式会社 2004-09-15 CN disclosed
CN-1494723-A Electrolytic capacitor and electrolyte for driving electrolytic capacitor 如碧空株式会社 2004-05-05 CN disclosed
CN-1155100-A Photosensitive composition and photosensitive lithographic printing plate using the same KONISHIROKU PHOTO IND (JP) 1997-07-23 CN disclosed
US-5275903-A Toners with liquid crystalline resins, colors and plasticizing XEROX CORPORATION (US) 1994-01-04 US disclosed