⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15096145 | 0.77 | — | — | |
| SCHEMBL23081026 | 0.74 | L3MBTL1 (0.31) | — | |
| SCHEMBL21693847 | 0.68 | — | — | |
| SCHEMBL6628720 | 0.68 | — | — | |
| SCHEMBL3459311 | 0.66 | NOS3 (0.36) | — | |
| SCHEMBL15096150 | 0.65 | MAOA (0.32) | — | |
| SCHEMBL18576657 | 0.62 | — | — | |
| SCHEMBL24815574 | 0.62 | — | — | |
| SCHEMBL25085558 | 0.61 | GNAI3 (0.36) | — | |
| SCHEMBL21544537 | 0.61 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8822520-B2 | Substituted bicyclic HCV inhibitors | PRESIDIO PHARMACEUTICALS, INC. (US) | 2014-09-02 | — | — | US | disclosed |
| US-20130178507-A1 | SUBSTITUTED BICYCLIC HCV INHIBITORS | PRESIDIO PHARMACEUTICALS, INC. (US) | 2013-07-11 | — | — | US | disclosed |