Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.32 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.32 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11030460 | 0.78 | GRIA1 (0.53) | CYP2C19KMT2AGRIA1GRIA3MAPT | |
| SCHEMBL6046222 | 0.78 | GRIA1 (0.53) | CYP2C19KMT2AGRIA1GRIA3MAPT | |
| SCHEMBL7497698 | 0.74 | LDHA (0.38) | LDHACYP2C19KMT2ACYP2C9CYP1A2 | |
| SCHEMBL9972719 | 0.70 | APAF1 (0.37) | MAPTCYP1A2BLMAPAF1KDM4E | |
| SCHEMBL13762701 | 0.70 | KMT2A (0.40) | LDHACYP2C19KMT2AMAPTMEN1 | |
| SCHEMBL18035901 | 0.69 | GRIA1 (0.49) | CYP2C19KMT2AGRIA1GRIA3MAPT | |
| SCHEMBL28619366 | 0.69 | ALOX15 (0.38) | LDHACYP2C19KMT2AMAPTMEN1 | |
| SCHEMBL10925736 | 0.68 | FOLH1 (0.37) | LDHACYP2C19KMT2ACYP1A2 | |
| SCHEMBL8331718 | 0.68 | GRIA1 (0.50) | KMT2AGRIA1GRIA3GRIA2GRIA4 | |
| SCHEMBL18035913 | 0.68 | GRIA1 (0.47) | CYP2C19KMT2AGRIA1GRIA3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2226329-B1 | Metal-containing platensimycin analogues | UNIV RUHR BOCHUM (DE) | 2013-07-10 | — | — | EP | disclosed |