Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 8/20 | 0.33 |
| ▸ | HTR7 | P34969 | 7/20 | 0.33 |
| ▸ | HTR2C | P28335 | 6/20 | 0.33 |
| ▸ | HTR1D | P28221 | 6/20 | 0.33 |
| ▸ | DRD1 | P21728 | 5/20 | 0.33 |
| ▸ | DRD4 | P21917 | 5/20 | 0.33 |
| ▸ | HRH2 | P25021 | 5/20 | 0.33 |
| ▸ | HTR1B | P28222 | 5/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.33 |
| ▸ | HRH1 | P35367 | 5/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.33 |
| ▸ | HTR5A | P47898 | 3/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD5 | P21918 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6400747 | 0.84 | ALDH1A1 (0.38) | DRD2ALDH1A1MAPTHTTGRM2 | |
| SCHEMBL21173696 | 0.82 | HTR1D (0.38) | HTR2BHTR7HTR2CHTR1DDRD1 | |
| SCHEMBL1509960 | 0.77 | HTR1D (0.47) | HTR2BHTR2CHTR1DDRD1HTR1B | |
| SCHEMBL8077290 | 0.74 | CYP2C9 (0.32) | HTR2BHTR2CHTR1DHTR1BFPR2 | |
| SCHEMBL1509908 | 0.73 | CYP2C9 (0.34) | DRD1DRD2ALDH1A1MAPTCNR2 | |
| SCHEMBL30201447 | 0.72 | HTR2C (0.35) | HTR2BHTR2CHTR1DHTR1BFPR2 | |
| SCHEMBL12140864 | 0.72 | HTR2C (0.35) | HTR2BHTR2CHTR1DHTR1BFPR2 | |
| SCHEMBL7858136 | 0.72 | HTR2C (0.35) | HTR2BHTR2CHTR1DHTR1BFPR2 | |
| SCHEMBL15803732 | 0.72 | MCHR1 (0.34) | HTR1DHTR1BALDH1A1MAPTHTT | |
| SCHEMBL8072011 | 0.72 | ALDH1A1 (0.39) | HTR2BDRD4DRD2HTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1731493-B1 | BENZENE DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY | CHISSO CORP (JP) | 2011-03-23 | — | — | EP | disclosed |
| EP-1731493-A1 | BENZENE DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY | CHISSO CORPORATION (JP) | 2006-12-13 | — | — | EP | disclosed |