Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 5/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862903 | 0.75 | ALDH1A1 (0.35) | DPP4 | |
| SCHEMBL13337392 | 0.73 | CTSL (0.41) | CTSKCTSL | |
| SCHEMBL19332413 | 0.69 | CTSL (0.36) | CTSKCTSL | |
| SCHEMBL11974296 | 0.68 | CTSK (0.32) | CTSKCTSL | |
| SCHEMBL82141 | 0.68 | CTSK (0.33) | CTSKCTSL | |
| SCHEMBL740875 | 0.67 | ALOX15 (0.33) | CTSKCTSL | |
| SCHEMBL1393426 | 0.67 | CTSK (0.37) | CTSKDPP4CTSL | |
| SCHEMBL782800 | 0.67 | CTSK (0.38) | CTSKCTSL | |
| SCHEMBL2312894 | 0.66 | MAPK1 (0.34) | — | |
| SCHEMBL27527940 | 0.66 | GRIN2B (0.34) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1882689-B1 | TRI- OR TETRA-SUBSTITUTED-3-AMINOPYRROLIDINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2013-07-10 | — | — | EP | disclosed |