Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.55 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.48 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15131923 | 0.90 | PAOX (0.55) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL20829925 | 0.84 | SLC6A5 (0.57) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL10490875 | 0.83 | SLC6A5 (0.42) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL12863577 | 0.83 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL7203302 | 0.83 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL7208464 | 0.83 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL7209833 | 0.83 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL7215984 | 0.83 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL7215946 | 0.83 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL17373920 | 0.83 | SLC6A5 (0.67) | SLC6A5PAOXKDM4AHIF1ATET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2793947-B1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | INNATE PHARMA (FR) | 2021-02-03 | — | — | EP | disclosed |
| US-10434180-B2 | Enzymatic conjugation of polypeptides | INNATE PHARMA (FR) | 2019-10-08 | — | — | US | disclosed |
| EP-3240573-B1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | INNATE PHARMA (FR) | 2019-03-20 | — | — | EP | disclosed |
| US-10132799-B2 | Screening of conjugated antibodies | INNATE PHARMA (FR) | 2018-11-20 | — | — | US | disclosed |
| US-20180071402-A1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | INNATE PHARMA (FR) | 2018-03-15 | — | — | US | disclosed |
| US-20180071402-A1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | INNATE PHARMA (FR) | 2018-03-15 | — | — | US | disclosed |
| US-9717803-B2 | Enzymatic conjugation of polypeptides | INNATE PHARMA (FR) | 2017-08-01 | — | — | US | disclosed |
| US-9717803-B2 | Enzymatic conjugation of polypeptides | INNATE PHARMA (FR) | 2017-08-01 | — | — | US | disclosed |
| US-9717803-B2 | Enzymatic conjugation of polypeptides | INNATE PHARMA (FR) | 2017-08-01 | — | — | US | disclosed |
| US-20160331842-A1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | ARARIS BIOTECH LTD (CH) | 2016-11-17 | — | — | US | disclosed |
| US-9427478-B2 | Enzymatic conjugation of polypeptides | INNATE PHARMA (FR) | 2016-08-30 | — | — | US | disclosed |
| US-20150346195-A1 | SCREENING OF CONJUGATED ANTIBODIES | ARARIS BIOTECH LTD (CH) | 2015-12-03 | — | — | US | disclosed |
| US-20150165064-A1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | ARARIS BIOTECH LTD (CH) | 2015-06-18 | — | — | US | disclosed |
| US-20130189287-A1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | PAUL SCHERRER INSTITUT | 2013-07-25 | — | — | US | disclosed |
| US-20130189287-A1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | PAUL SCHERRER INSTITUT | 2013-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130189287-A1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | DNPEP, ENPEP, PEPD | SLC6A5 4062/4885PAOX 899/4885KDM4A 3624/4885 |
| US-20180071402-A1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | DNPEP, ENPEP, PEPD | SLC6A5 4005/4885PAOX 891/4885KDM4A 3523/4885 |
| US-10434180-B2 | Enzymatic conjugation of polypeptides | DNPEP, ENPEP, PEPD | SLC6A5 4077/4885PAOX 814/4885KDM4A 3225/4885 |
| US-10132799-B2 | Screening of conjugated antibodies | FCGR2A, TGM2, TGM6 | SLC6A5 864/4885PAOX 3882/4885KDM4A 2321/4885 |
| US-20150346195-A1 | SCREENING OF CONJUGATED ANTIBODIES | FCGR2A, TGM2, TGM6 | SLC6A5 864/4885PAOX 3882/4885KDM4A 2321/4885 |
| US-20160331842-A1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | DNPEP, ENPEP, PEPD | SLC6A5 4077/4885PAOX 814/4885KDM4A 3225/4885 |
| US-20150165064-A1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | DNPEP, ENPEP, PEPD | SLC6A5 4077/4885PAOX 814/4885KDM4A 3225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.