Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.50 |
| ▸ | MPEG1 | Q2M385 | 4/20 | 0.50 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 5/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2404064 | 0.83 | HKDC1 (0.50) | ALOX5MPEG1HKDC1KDM4EMEN1 | |
| SCHEMBL1960919 | 0.83 | HKDC1 (0.54) | ALOX5MPEG1HKDC1KDM4EMEN1 | |
| SCHEMBL197917 | 0.80 | HKDC1 (0.56) | ALOX5MPEG1HKDC1KDM4EMEN1 | |
| SCHEMBL5983372 | 0.78 | HKDC1 (0.72) | ALOX5MPEG1HKDC1KDM4EMEN1 | |
| SCHEMBL31189916 | 0.75 | HKDC1 (0.50) | ALOX5HKDC1KDM4EMEN1USP2 | |
| SCHEMBL789116 | 0.75 | ALOX5 (0.67) | ALOX5MPEG1 | |
| SCHEMBL5154804 | 0.73 | XIAP (0.54) | ALOX5MPEG1KDM4EMEN1USP2 | |
| SCHEMBL5163654 | 0.72 | HKDC1 (0.69) | ALOX5MPEG1HKDC1KDM4EMEN1 | |
| SCHEMBL9578683 | 0.72 | ALOX5 (0.88) | ALOX5MPEG1 | |
| SCHEMBL3417111 | 0.69 | HKDC1 (0.56) | ALOX5HKDC1KDM4EMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957214-B2 | Multifunctional radical quenchers | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-05-01 | — | — | US | disclosed |
| US-9447010-B2 | Method for preparing a herbicidal compound | BANGOR UNIVERSITY (GB) | 2016-09-20 | — | — | US | disclosed |
| US-20150274628-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-10-01 | — | — | US | disclosed |
| WO-2013121190-A1 | METHOD FOR PREPARING A HERBICIDAL COMPOUND | BANGOR UNIVERSITY (GB) | 2013-08-22 | — | — | WO | disclosed |
| CN-101627983-B | Pharmaceutical composition for inhibiting angiogenesis and application thereof | GRAPE KING INC | 2012-03-14 | — | — | CN | disclosed |
| CN-101627983-A | Pharmaceutical composition for inhibiting angiogenesis and application thereof | GRAPE KING INC | 2010-01-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274628-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS | SQOR, UQCRC1, PRDX5 | ALOX5 779/4885MPEG1 2716/4885HKDC1 3100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.