Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 6/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5983372 | 0.84 | HKDC1 (0.72) | HKDC1KDM4EMEN1USP2TP53 | |
| SCHEMBL5163654 | 0.82 | HKDC1 (0.69) | HKDC1KDM4EMEN1USP2TP53 | |
| SCHEMBL31189916 | 0.80 | HKDC1 (0.50) | HKDC1KDM4EMEN1USP2TP53 | |
| SCHEMBL2404064 | 0.80 | HKDC1 (0.50) | HKDC1KDM4EMEN1USP2TP53 | |
| SCHEMBL15212939 | 0.80 | ALOX5 (0.50) | HKDC1KDM4EMEN1USP2TP53 | |
| SCHEMBL3417111 | 0.73 | HKDC1 (0.56) | HKDC1KDM4EMEN1USP2TP53 | |
| SCHEMBL49737 | 0.73 | ERBB2 (0.62) | HKDC1KDM4EMEN1USP2TP53 | |
| SCHEMBL3413590 | 0.71 | HKDC1 (1.00) | HKDC1KDM4EMEN1USP2TP53 | |
| SCHEMBL28856262 | 0.71 | ERBB2 (0.59) | HKDC1KDM4EMEN1USP2TP53 | |
| SCHEMBL11025815 | 0.70 | MAPT (0.50) | HKDC1KDM4EMEN1USP2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180128767-A1 | Small Volume In Vitro Analyte Sensor | ABBOTT DIABETES CARE INC. (US) | 2018-05-10 | — | — | US | disclosed |
| US-9891185-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2018-02-13 | — | — | US | disclosed |
| US-9662057-B2 | Integrated sample acquisition and analyte measurement method | ABBOTT DIABETES CARE INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160334356-A1 | Small Volume In Vitro Analyte Sensor | THERASENSE, INC. | 2016-11-17 | — | — | US | disclosed |
| US-20160235350-A1 | Integrated Sample Acquisition and Analyte Measurement Device | THERASENSE, INC. | 2016-08-18 | — | — | US | disclosed |
| US-9341591-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-9316609-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-9291592-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2016-03-22 | — | — | US | disclosed |
| US-9271669-B2 | Method for integrated sample acquisition and analyte measurement device | ABBOTT DIABETES CARE INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-9234863-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-20030199744-A1 | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator | THERASENSE, INC. (US) | 2003-10-23 | — | — | US | disclosed |
| US-6618934-B1 | Method of manufacturing small volume in vitro analyte sensor | THERASENSE, INC. | 2003-09-16 | — | — | US | disclosed |
| US-6592745-B1 | Analytical sensors for the detection of bioanalytes in a small volume sample; to monitor glucose in diabetic patients and lactate during critical care | THERASENSE, INC. | 2003-07-15 | — | — | US | disclosed |
| US-6591125-B1 | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator | THERASENSE, INC. | 2003-07-08 | — | — | US | disclosed |
| US-6461496-B1 | BLOOD GLUCOSE | THERASENSE, INC. | 2002-10-08 | — | — | US | disclosed |
| US-6338790-B1 | DETECTION OF BIOANALYTES IN A SMALL VOLUME SAMPLE; CONCENTRATION OF A BIOMOLECULE, SUCH AS GLUCOSE OR LACTATE, USING TECHNIQUES SUCH AS COULOMETRY, AMPEROMETRY, AND POTENTIOMETRY. AN ENZYME CAPABLE OF CATALYZING THE | THERASENSE, INC. | 2002-01-15 | — | — | US | disclosed |
| CN-1322254-A | Small volume in vitro analytical sensor containing diffusible or non-leachable redox mediator | THERASENSE INC (US) | 2001-11-14 | — | — | CN | disclosed |
| US-6299757-B1 | ANALYTICAL SENSORS FOR THE DETECTION OF BIOANALYTES; ESPECIALLY MONITORING GLUCOSE LEVELS IN DIABETIC PATIENTS | THERASENSE, INC. | 2001-10-09 | — | — | US | disclosed |
| EP-1119637-A1 | SMALL VOLUME $i(IN VITRO) ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR | Therasense, Inc. (US) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000020626-A1 | SMALL VOLUME IN VITRO ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR | THERASENSE, INC. (US) | 2000-04-13 | — | — | WO | disclosed |