Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.46 |
| ▸ | MPEG1 | Q2M385 | 4/20 | 0.46 |
| ▸ | IDO1 | P14902 | 6/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15212939 | 0.83 | ALOX5 (0.50) | HKDC1KDM4EMEN1USP2TP53 | |
| SCHEMBL1960919 | 0.83 | HKDC1 (0.54) | HKDC1KDM4EMEN1USP2TP53 | |
| SCHEMBL197917 | 0.80 | HKDC1 (0.56) | HKDC1KDM4EMEN1USP2TP53 | |
| SCHEMBL5163654 | 0.77 | HKDC1 (0.69) | HKDC1KDM4EMEN1USP2TP53 | |
| SCHEMBL5983372 | 0.74 | HKDC1 (0.72) | HKDC1KDM4EMEN1USP2TP53 | |
| SCHEMBL5712778 | 0.73 | XIAP (0.48) | KDM4EMEN1USP2TP53CYP3A4 | |
| SCHEMBL755506 | 0.73 | ALDH1A1 (0.48) | KDM4EMEN1USP2TP53CYP3A4 | |
| SCHEMBL9578778 | 0.72 | ALOX5 (0.68) | ALOX5MPEG1 | |
| SCHEMBL31189916 | 0.71 | HKDC1 (0.50) | HKDC1KDM4EMEN1USP2TP53 | |
| SCHEMBL789116 | 0.71 | ALOX5 (0.67) | ALOX5MPEG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | L'OREAL S.A. | 2007-06-14 | — | — | US | claimed |
| EP-1434552-A1 | METHOD FOR DYEING KERATINOUS FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-07-07 | — | — | EP | claimed |
| US-6635090-B1 | Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative | L'OREAL, S.A. (FR) | 2003-10-21 | — | — | US | claimed |
| WO-2003030841-A1 | METHOD FOR DYEING KERATINOUS FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| US-6458168-B1 | Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative | L'OREAL S.A. (FR) | 2002-10-01 | — | — | US | claimed |
| US-6451067-B1 | HAIR DYE MIXTURE | L'OREAL S.A. (FR) | 2002-09-17 | — | — | US | claimed |
| EP-0498707-B1 | Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent | OREAL (FR) | 1995-08-02 | — | — | EP | claimed |
| EP-0498707-A1 | Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent | L'OREAL (FR) | 1992-08-12 | — | — | EP | claimed |
| EP-0279988-B1 | DIGITAL THRESHOLD COLOUR CONTROL SYSTEM | ENZYMATICS, INC. (US) | 1991-04-24 | — | — | EP | claimed |
| EP-0279988-A1 | Digital threshold colour control system | ENZYMATICS, INC. (US) | 1988-08-31 | — | — | EP | claimed |
| EP-3843696-B1 | PROCESS AND COMPOSITION FOR COLORING KERATIN FIBERS | OREAL (FR) | 2025-04-09 | — | — | EP | disclosed |
| CN-113164346-B | Composition for keratin fibres comprising a direct dye | 莱雅公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-112601515-B | Method and composition for coloring keratin fibers | 莱雅公司 | 2024-04-05 | — | — | CN | disclosed |
| WO-2024048429-A1 | COSMETIC PROCESS USING PARTICLE WITH MICROPROTRUSION | L'OREAL (FR) | 2024-03-07 | — | — | WO | disclosed |
| WO-2023228870-A1 | COMPOSITION FOR COLORING KERATIN FIBERS | L'OREAL (FR) | 2023-11-30 | — | — | WO | disclosed |
| EP-0498707-B1 | Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent | OREAL (FR) | 1995-08-02 | — | — | EP | disclosed |
| EP-0659397-A1 | Process for direct coloration of human keratinic fibers by natural dyes and water steam | L'OREAL (FR) | 1995-06-28 | — | — | EP | disclosed |
| US-5275626-A | Hair dyes | L'OREAL (FR) | 1994-01-04 | — | — | US | disclosed |
| EP-0498707-A1 | Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent | L'OREAL (FR) | 1992-08-12 | — | — | EP | disclosed |
| US-4867751-A | HAIR DYES | L'OREAL (FR) | 1989-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | KRT18, NDUFB5, NDUFB7 | HKDC1 159/4885KDM4E 440/4885MEN1 2976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.