Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.79 |
| ▸ | MGAM | O43451 | 1/20 | 0.79 |
| ▸ | SI | P14410 | 1/20 | 0.79 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 9/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid Diethyl Ester SCHEMBL23042850 | 0.89 | GAA (0.88) | GAAMGAMSIMGAM2ALDH1A1 | |
| Malonic Acid Diethyl Ester SCHEMBL8636 | 0.89 | GAA (1.00) | GAAMGAMSIMGAM2ALDH1A1 | |
| Malonic Acid Diethyl Ester SCHEMBL1331187 | 0.89 | GAA (1.00) | GAAMGAMSIMGAM2ALDH1A1 | |
| Malonic Acid Diethyl Ester SCHEMBL1331824 | 0.89 | GAA (1.00) | GAAMGAMSIMGAM2ALDH1A1 | |
| Malonic Acid Diethyl Ester SCHEMBL1330550 | 0.89 | GAA (1.00) | GAAMGAMSIMGAM2ALDH1A1 | |
| Malonic Acid Diethyl Ester SCHEMBL1864301 | 0.89 | GAA (1.00) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL12764772 | 0.88 | GAA (0.61) | GAAMGAMSIMGAM2ALDH1A1 | |
| Malonic Acid Diethyl Ester SCHEMBL3670061 | 0.86 | GAA (0.94) | GAAMGAMSIMGAM2ALDH1A1 | |
| Malonic Acid Diethyl Ester SCHEMBL4334303 | 0.86 | GAA (0.94) | GAAMGAMSIMGAM2ALDH1A1 | |
| Malonic Acid Diethyl Ester SCHEMBL4939828 | 0.86 | GAA (0.94) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183170-A1 | 1,1-DISUBSTITUTED ETHYLENE PROCESS | OPTMED, INC. | 2023-06-15 | — | — | US | disclosed |
| US-20200223790-A1 | IMPROVED 1,1-DISUBSTITUTED ETHYLENE PROCESS | OPTMED, INC. (US) | 2020-07-16 | — | — | US | disclosed |
| US-10597355-B2 | 1,1-disubstituted ethylene process | OPTMED, INC. (US) | 2020-03-24 | — | — | US | disclosed |
| EP-2807142-B1 | IMPROVED METHYLIDENE MALONATE PROCESS | OPTMED INC (US) | 2019-09-04 | — | — | EP | disclosed |
| EP-2464636-B1 | PROCESS FOR THE SYNTHESIS OF 2,4-DIOXOTETRAHYDROFURAN-3-CARBOXYLATES | BAYER IP GMBH (DE) | 2015-07-08 | — | — | EP | disclosed |
| US-20150166471-A1 | 1, 1-DISUBSTITUTED ETHYLENE PROCESS | H.B. FULLER COMPANY | 2015-06-18 | — | — | US | disclosed |
| US-20150158807-A1 | METHYLIDENE MALONATE PROCESS | H.B. FULLER COMPANY, AS COLLATERAL AGENT | 2015-06-11 | — | — | US | disclosed |
| US-20130197263-A1 | 1,1-DISUBSTITUTED ETHYLENE PROCESS | OPTMED, INC. (US) | 2013-08-01 | — | — | US | disclosed |
| US-20130197264-A1 | METHYLIDENE MALONATE PROCESS | OPTMED, INC. (US) | 2013-08-01 | — | — | US | disclosed |
| US-8318955-B2 | Process for preparing 2,4-dioxotetrahydrofuran-3-carboxylates | BAYER CROPSCIENCE AG (DE) | 2012-11-27 | — | — | US | disclosed |
| US-8318955-B2 | Process for preparing 2,4-dioxotetrahydrofuran-3-carboxylates | BAYER CROPSCIENCE AG (DE) | 2012-11-27 | — | — | US | disclosed |
| US-20110060147-A1 | Process for preparing 2,4-dioxotetrahydrofuran-3-carboxylates | BAYER CROPSCIENCE AG (DE) | 2011-03-10 | — | — | US | disclosed |
| US-20110060147-A1 | Process for preparing 2,4-dioxotetrahydrofuran-3-carboxylates | BAYER CROPSCIENCE AG (DE) | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197263-A1 | 1,1-DISUBSTITUTED ETHYLENE PROCESS | ECE1, UBE2E1, ESR1 | GAA 1338/4885MGAM 428/4885SI 1936/4885 |
| US-20230183170-A1 | 1,1-DISUBSTITUTED ETHYLENE PROCESS | ME1, MMAB, CA6 | GAA 2327/4885MGAM 81/4885SI 1294/4885 |
| US-20200223790-A1 | IMPROVED 1,1-DISUBSTITUTED ETHYLENE PROCESS | ME1, MMAB, CA6 | GAA 1856/4885MGAM 42/4885SI 1243/4885 |
| US-20130197264-A1 | METHYLIDENE MALONATE PROCESS | ME1, MAL2, MPHOSPH6 | GAA 1153/4885MGAM 4/4885SI 622/4885 |
| US-20110060147-A1 | Process for preparing 2,4-dioxotetrahydrofuran-3-carboxylates | HDHD5, HACL2, IDUA | GAA 379/4885MGAM 468/4885SI 1432/4885 |
| US-10597355-B2 | 1,1-disubstituted ethylene process | ME1, MMAB, CA6 | GAA 2327/4885MGAM 81/4885SI 1294/4885 |
| US-20150166471-A1 | 1, 1-DISUBSTITUTED ETHYLENE PROCESS | ECE1, UBE2E1, ESR1 | GAA 1338/4885MGAM 428/4885SI 1936/4885 |
| US-20150158807-A1 | METHYLIDENE MALONATE PROCESS | ME1, MAL2, MPHOSPH6 | GAA 1153/4885MGAM 4/4885SI 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.